We firstly measured the swelling of single trabeculae from human femur heads during water imbibition. Since the swelling is caused by water diffusing from external surfaces to the core of the sample, by measuring the sample swelling over time, we obtained direct information about the transport of fluids through the intimate constituents of bone, where the mineralization process takes place. We developed an apparatus to measure the free expansion of the tissue during the imbibition. In particular, we measured the swelling along three natural axes (length L, width W, and thickness T) of plate-like trabeculae. For this aim, we developed a 3D analytical model of the water uptake by the sample that was performed according to Fickian transport mechanism. The results were then utilized to predict the swelling over time along the three sample directions (L, W, T) and the apparent diffusion coefficients D-T, D-W, and D-L..
Experimental study of diffusion coefficients of water through the collagen: apatite porosity in human trabecular bone tissue / Marinozzi, Franco; Bini, Fabiano; Quintino, Alessandro; Corcione, Massimo; Andrea, Marinozzi. - In: BIOMED RESEARCH INTERNATIONAL. - ISSN 2314-6133. - STAMPA. - 2014:(2014). [10.1155/2014/796519]
Experimental study of diffusion coefficients of water through the collagen: apatite porosity in human trabecular bone tissue
MARINOZZI, Franco
;BINI, FABIANO;QUINTINO, ALESSANDRO;CORCIONE, Massimo;
2014
Abstract
We firstly measured the swelling of single trabeculae from human femur heads during water imbibition. Since the swelling is caused by water diffusing from external surfaces to the core of the sample, by measuring the sample swelling over time, we obtained direct information about the transport of fluids through the intimate constituents of bone, where the mineralization process takes place. We developed an apparatus to measure the free expansion of the tissue during the imbibition. In particular, we measured the swelling along three natural axes (length L, width W, and thickness T) of plate-like trabeculae. For this aim, we developed a 3D analytical model of the water uptake by the sample that was performed according to Fickian transport mechanism. The results were then utilized to predict the swelling over time along the three sample directions (L, W, T) and the apparent diffusion coefficients D-T, D-W, and D-L..File | Dimensione | Formato | |
---|---|---|---|
Marinozzi_experimental-study_2014.pdf
solo utenti autorizzati
Note: http://dx.doi.org/10.1155/2014/796519
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Creative commons
Dimensione
2.39 MB
Formato
Adobe PDF
|
2.39 MB | Adobe PDF | Contatta l'autore |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.