We have studied beating mouse cardiac syncytia in vitro in order to assess the inotropic, ergotropic, and chronotropic effects of both increasing and decreasing hydrostatic pressures. In particular, we have performed an image processing analysis to evaluate the kinematics and the dynamics of those pressure-loaded beating syncytia starting from the video registration of their contraction movement. By this analysis, we have verified the Frank-Starling law of the heart in in vitro beating cardiac syncytia and we have obtained their geometrical-functional classification
Modulation of the cardiomyocyte contractile function inside a hydrostatic pressure bioreactor: verification of the Frank-Starling law / L., Fassina; G., Magenes; R., Gimmelli; Naro, Fabio. - In: BIOMED RESEARCH INTERNATIONAL. - ISSN 2314-6133. - ELETTRONICO. - 2015:(2015), pp. 1-7. [10.1155/2015/542105]
Modulation of the cardiomyocyte contractile function inside a hydrostatic pressure bioreactor: verification of the Frank-Starling law
NARO, Fabio
2015
Abstract
We have studied beating mouse cardiac syncytia in vitro in order to assess the inotropic, ergotropic, and chronotropic effects of both increasing and decreasing hydrostatic pressures. In particular, we have performed an image processing analysis to evaluate the kinematics and the dynamics of those pressure-loaded beating syncytia starting from the video registration of their contraction movement. By this analysis, we have verified the Frank-Starling law of the heart in in vitro beating cardiac syncytia and we have obtained their geometrical-functional classification| File | Dimensione | Formato | |
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