After the recent discovery of various mutations of theCALRgene,,10% of adult patients with essential thrombocythemia (ET) orprimary myelofibrosis carry no identified molecular markers.1,2More rarely, ET may occur also in children and adolescents.3Weevaluated, by Sanger sequencing, the mutation status of exon 9 oftheCALRgene in 34 ET patients younger than 20 years of age atdiagnosis (median age, 15 years; range, 1-19 years). The study wasapproved by the Institutional Ethic Committees

CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence / Giona, Fiorina; Teofili, L; Capodimonti, S; Laurino, M; Martini, M; Marzella, D; Palumbo, G; Diverio, D; Foa, Roberto; Larocca, L. M.. - In: BLOOD. - ISSN 0006-4971. - 123:33(2014), pp. 3677-3679. [10.1182/blood-2014-04-572040]

CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence.

GIONA, Fiorina;FOA, Roberto;
2014

Abstract

After the recent discovery of various mutations of theCALRgene,,10% of adult patients with essential thrombocythemia (ET) orprimary myelofibrosis carry no identified molecular markers.1,2More rarely, ET may occur also in children and adolescents.3Weevaluated, by Sanger sequencing, the mutation status of exon 9 oftheCALRgene in 34 ET patients younger than 20 years of age atdiagnosis (median age, 15 years; range, 1-19 years). The study wasapproved by the Institutional Ethic Committees
2014
thrombocythemia diagnosed in childhoodand adolescence
01 Pubblicazione su rivista::01a Articolo in rivista
CALR mutations in patients with essential thrombocythemia diagnosed in childhood and adolescence / Giona, Fiorina; Teofili, L; Capodimonti, S; Laurino, M; Martini, M; Marzella, D; Palumbo, G; Diverio, D; Foa, Roberto; Larocca, L. M.. - In: BLOOD. - ISSN 0006-4971. - 123:33(2014), pp. 3677-3679. [10.1182/blood-2014-04-572040]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/577399
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