This review describes the principles and instrumentation for the screening of asymmetric reactions by mass spectrometry. These techniques witnessed a significant advancement in the last few years. Although some of them are still at the proof-of-concept development stage, several applications might be foreseen in the field of combinatorial, high-throughput parallel catalyst screening.

Determination of Enantioselectivity and Enantiomeric Excess by Mass Spectrometry in the Absence of Chiral Chromatographic Separation: An Overview / Piovesana, Susy; Samperi, Roberto; Lagana', Aldo; Bella, Marco. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 19:35(2013), pp. 11478-11494. [10.1002/chem.201300233]

Determination of Enantioselectivity and Enantiomeric Excess by Mass Spectrometry in the Absence of Chiral Chromatographic Separation: An Overview

PIOVESANA, SUSY;SAMPERI, Roberto;LAGANA', Aldo;BELLA, Marco
2013

Abstract

This review describes the principles and instrumentation for the screening of asymmetric reactions by mass spectrometry. These techniques witnessed a significant advancement in the last few years. Although some of them are still at the proof-of-concept development stage, several applications might be foreseen in the field of combinatorial, high-throughput parallel catalyst screening.
2013
alpha-hydroxy acids; amino-acids; analytical chemistry; catalysts; differentiation; enantiomeric excess; enantioselectivity; gas-phase; kinetic method; mass spectrometry; mixtures; quantification; resolution
01 Pubblicazione su rivista::01a Articolo in rivista
Determination of Enantioselectivity and Enantiomeric Excess by Mass Spectrometry in the Absence of Chiral Chromatographic Separation: An Overview / Piovesana, Susy; Samperi, Roberto; Lagana', Aldo; Bella, Marco. - In: CHEMISTRY-A EUROPEAN JOURNAL. - ISSN 0947-6539. - STAMPA. - 19:35(2013), pp. 11478-11494. [10.1002/chem.201300233]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/524530
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