Background: Tumor cells that are identified in transit within the blood stream are referred to as circulating tumor cells (CTCs); a fraction of these are thought to be viable metastatic precursors capable of initiating a clonal metastatic lesion. CTC could be used as non-invasive marker for monitoring drug sensitivity or resistance and select cancer patients who are candidates for early systemic antimetastatic therapy. Identifying CTCs in neoplastic patients could be also an independent prognostic factor for patients at risk for recurrence or metastasis.
Clinical significance of circulating tumor cells in colon and breast solid neoplasms / F., Ricci; V., Bordoni; Pugliese, Federico; F., Borrini; Merlini, Gianluca; Forcione, Annarita; Mingazzini, Pietro; Izzo, Luciano; Bolognese, Antonio. - In: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0748-7983. - 38:10(2012), pp. 982-983. (Intervento presentato al convegno XXXV congresso nazionale SICO tenutosi a Torino nel 14-16 giugno 2012) [10.1016/j.ejso.2012.07.029].
Clinical significance of circulating tumor cells in colon and breast solid neoplasms
PUGLIESE, FEDERICO;MERLINI, GIANLUCA;FORCIONE, Annarita;MINGAZZINI, Pietro;IZZO, Luciano;BOLOGNESE, Antonio
2012
Abstract
Background: Tumor cells that are identified in transit within the blood stream are referred to as circulating tumor cells (CTCs); a fraction of these are thought to be viable metastatic precursors capable of initiating a clonal metastatic lesion. CTC could be used as non-invasive marker for monitoring drug sensitivity or resistance and select cancer patients who are candidates for early systemic antimetastatic therapy. Identifying CTCs in neoplastic patients could be also an independent prognostic factor for patients at risk for recurrence or metastasis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
