The circadian rhythm of serum angiotensin-converting enzyme (ACE) activity was investigated in pregnant women with normal and pre-eclamptic gestation. The chronobiological approach was able to document the occurrence of a circadian rhythm for serum ACE activity in normal pregnancy. Such a rhythm is characterized by a decreased mesor and amplitude and a shifted crest. The circadian rhythm for serum ACE activity was not detectable in pre-eclamptic pregnancy. Such an abrogation is accompanied by a negligible decrease of mesor suggesting the occurrence of a relative hyperACEemia. This disorder could play a role in pregnancy-induced hypertension.
Serum angiotensin-converting enzyme activity in pre-eclamptic pregnancy: Evidence for a relative hypermesorACEemia / Cugini, Pietro; Letizia, Claudio; L., Battisti Di Palma; Caserta, Donatella; Moscarini, Massimo; Scavo, Domenico. - In: ENZYME. - ISSN 0013-9432. - STAMPA. - 43:3(1990), pp. 113-121.
Serum angiotensin-converting enzyme activity in pre-eclamptic pregnancy: Evidence for a relative hypermesorACEemia
CUGINI, Pietro;LETIZIA, Claudio;CASERTA, Donatella;MOSCARINI, Massimo;SCAVO, Domenico
1990
Abstract
The circadian rhythm of serum angiotensin-converting enzyme (ACE) activity was investigated in pregnant women with normal and pre-eclamptic gestation. The chronobiological approach was able to document the occurrence of a circadian rhythm for serum ACE activity in normal pregnancy. Such a rhythm is characterized by a decreased mesor and amplitude and a shifted crest. The circadian rhythm for serum ACE activity was not detectable in pre-eclamptic pregnancy. Such an abrogation is accompanied by a negligible decrease of mesor suggesting the occurrence of a relative hyperACEemia. This disorder could play a role in pregnancy-induced hypertension.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
