The aim of this paper was to investigate the effect of glycerol on experimental endolymphatic hydrops in guinea-pigs. The right endolymphatic sac and duct were obliterated through an extradural posterior fossa approach. Some animals received a 3 g/kg dose of glycerol for a period of 7 days, whereas others received the same dose for 30 days. The activity of glycerol was studied by investigating the volumetric changes in the scala media determined with a computerized planimeter. Glycerol induced a significant reduction of the hydrops showing its effectiveness and suggesting a strial metabolic response.

The effect of glycerol on the guinea-pig hydropic ear / Magliulo, Giuseppe; Ungari, C; DELLA ROCCA, Carlo; Muscatello, M; Vingolo, G.. - In: CLINICAL OTOLARYNGOLOGY. - ISSN 0307-7772. - STAMPA. - 16(5):5(1991), pp. 483-487. [10.1111/j.1365-2273.1991.tb01045.x]

The effect of glycerol on the guinea-pig hydropic ear.

DELLA ROCCA, Carlo;
1991

Abstract

The aim of this paper was to investigate the effect of glycerol on experimental endolymphatic hydrops in guinea-pigs. The right endolymphatic sac and duct were obliterated through an extradural posterior fossa approach. Some animals received a 3 g/kg dose of glycerol for a period of 7 days, whereas others received the same dose for 30 days. The activity of glycerol was studied by investigating the volumetric changes in the scala media determined with a computerized planimeter. Glycerol induced a significant reduction of the hydrops showing its effectiveness and suggesting a strial metabolic response.
1991
guinea pig; endolymphatic hydrops; glycerol
01 Pubblicazione su rivista::01a Articolo in rivista
The effect of glycerol on the guinea-pig hydropic ear / Magliulo, Giuseppe; Ungari, C; DELLA ROCCA, Carlo; Muscatello, M; Vingolo, G.. - In: CLINICAL OTOLARYNGOLOGY. - ISSN 0307-7772. - STAMPA. - 16(5):5(1991), pp. 483-487. [10.1111/j.1365-2273.1991.tb01045.x]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/47456
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