The title compounds, valuable chiral synthons for the synthesis of biologically active compounds, have been prepared in good yield and with high stereoselectivity through palladium-catalyzed heteroannulation of 2-iodophenol or 2-iodo-N-mesylaniline with enantiomerically pure or enriched alpha-arylpropargylamines. (C) 2000 Elsevier Science Ltd. All rights reserved.
Stereoselective synthesis of alpha-aryl-2-benzofuranmethanamines and alpha-aryl-1H-indole-2-methanamines through palladium-mediated annulation of chiral alpha-arylpropargylamines / F., Messina; M., Botta; F., Corelli; Villani, Claudio. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 11:(2000), pp. 1681-1685. [10.1016/S0957-4166(00)00131-2]
Stereoselective synthesis of alpha-aryl-2-benzofuranmethanamines and alpha-aryl-1H-indole-2-methanamines through palladium-mediated annulation of chiral alpha-arylpropargylamines
VILLANI, Claudio
2000
Abstract
The title compounds, valuable chiral synthons for the synthesis of biologically active compounds, have been prepared in good yield and with high stereoselectivity through palladium-catalyzed heteroannulation of 2-iodophenol or 2-iodo-N-mesylaniline with enantiomerically pure or enriched alpha-arylpropargylamines. (C) 2000 Elsevier Science Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
