Fat, xylose and vitamin E absorption was studied in twenty homozygous beta-thalasemic patients with low tocopherol levels. While fat and xylose absorption was normal, vitamin E absorption was decreased in comparison to normal controls. The oral administration of tocopherol in eight of twenty patients studied failed to increase the serum vitamin E levels. On the other hand, an increase was found in five patients in whom vitamin E was administrated parenterally. The results of this study show that vitamin E malabsorption is present in homozygous beta-thalassemic patients. This could explain at least in part, their low serum and erythrocyte levels and the increased lipid membrane per oxidation with consequent hyperhemolysis.

Intestinal absorption of tocopherols in homozygous beta-thalassemia. A study of twenty patients / O., Giardini; G., Pratesi; M., Antimi; D., Bandino; Lubrano, Riccardo; I., Silvi; M., Qaddourah; S., Khashan. - In: HAEMATOLOGICA. - ISSN 0390-6078. - STAMPA. - 69:2(1984), pp. 127-132.

Intestinal absorption of tocopherols in homozygous beta-thalassemia. A study of twenty patients

LUBRANO, Riccardo;
1984

Abstract

Fat, xylose and vitamin E absorption was studied in twenty homozygous beta-thalasemic patients with low tocopherol levels. While fat and xylose absorption was normal, vitamin E absorption was decreased in comparison to normal controls. The oral administration of tocopherol in eight of twenty patients studied failed to increase the serum vitamin E levels. On the other hand, an increase was found in five patients in whom vitamin E was administrated parenterally. The results of this study show that vitamin E malabsorption is present in homozygous beta-thalassemic patients. This could explain at least in part, their low serum and erythrocyte levels and the increased lipid membrane per oxidation with consequent hyperhemolysis.
1984
01 Pubblicazione su rivista::01a Articolo in rivista
Intestinal absorption of tocopherols in homozygous beta-thalassemia. A study of twenty patients / O., Giardini; G., Pratesi; M., Antimi; D., Bandino; Lubrano, Riccardo; I., Silvi; M., Qaddourah; S., Khashan. - In: HAEMATOLOGICA. - ISSN 0390-6078. - STAMPA. - 69:2(1984), pp. 127-132.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/455001
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