MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information.

Improving your target-template alignment with MODalign / Barbato, Alessandro; P., Benkert; T., Schwede; Tramontano, Anna; Kosinski, Jan. - In: BIOINFORMATICS. - ISSN 1367-4803. - 28:7(2012), pp. 1038-1039. [10.1093/bioinformatics/bts070]

Improving your target-template alignment with MODalign

BARBATO, ALESSANDRO;TRAMONTANO, ANNA;KOSINSKI, JAN
2012

Abstract

MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information.
2012
01 Pubblicazione su rivista::01a Articolo in rivista
Improving your target-template alignment with MODalign / Barbato, Alessandro; P., Benkert; T., Schwede; Tramontano, Anna; Kosinski, Jan. - In: BIOINFORMATICS. - ISSN 1367-4803. - 28:7(2012), pp. 1038-1039. [10.1093/bioinformatics/bts070]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/452841
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