A data set of 16 autosomal STRs (the 13 CODIS loci plus HumCD4, HumFES, HumF13A1) was obtained in a sample of 52 unrelated Hutus from Rwanda. Genotypes at all loci met Hardy-Weinberg expectations with the exception of HumCSF1PO. No significant evidence of association across alleles at independent loci was obtained. Statistical parameters demonstrated the forensic usefulness of the analysed systems (combined PE=0.9999996, combined PD=1:2.27x10(18)). Pairwise comparisons showed that the Hutu gene pool differs substantially from that of other Bantu-speaking populations suggesting the use of ethnic-specific population databases in forensic casework analysis. The introduction of a non-negligible bias was confirmed by calculating the differences between multiple-locus profile frequencies of western and eastern Bantoids using local and non-local reference databases.

Variation at 16 STR loci in Rwandans (Hutu) and implications on profile frequency estimation in Bantu-speakers / S., Tofanelli; I., Boschi; S., Bertoneri; Coia, Valentina; L., Taglioli; M. G., Franceschi; DESTRO-BISOL, Giovanni; V., Pascali; G., Paoli. - In: INTERNATIONAL JOURNAL OF LEGAL MEDICINE. - ISSN 0937-9827. - STAMPA. - 117:2(2003), pp. 121-126. [10.1007/s00414-002-0349-0]

Variation at 16 STR loci in Rwandans (Hutu) and implications on profile frequency estimation in Bantu-speakers

COIA, Valentina;DESTRO-BISOL, Giovanni;
2003

Abstract

A data set of 16 autosomal STRs (the 13 CODIS loci plus HumCD4, HumFES, HumF13A1) was obtained in a sample of 52 unrelated Hutus from Rwanda. Genotypes at all loci met Hardy-Weinberg expectations with the exception of HumCSF1PO. No significant evidence of association across alleles at independent loci was obtained. Statistical parameters demonstrated the forensic usefulness of the analysed systems (combined PE=0.9999996, combined PD=1:2.27x10(18)). Pairwise comparisons showed that the Hutu gene pool differs substantially from that of other Bantu-speaking populations suggesting the use of ethnic-specific population databases in forensic casework analysis. The introduction of a non-negligible bias was confirmed by calculating the differences between multiple-locus profile frequencies of western and eastern Bantoids using local and non-local reference databases.
2003
codis; str-profiles; hutu; bantu-speakers; rwanda
01 Pubblicazione su rivista::01a Articolo in rivista
Variation at 16 STR loci in Rwandans (Hutu) and implications on profile frequency estimation in Bantu-speakers / S., Tofanelli; I., Boschi; S., Bertoneri; Coia, Valentina; L., Taglioli; M. G., Franceschi; DESTRO-BISOL, Giovanni; V., Pascali; G., Paoli. - In: INTERNATIONAL JOURNAL OF LEGAL MEDICINE. - ISSN 0937-9827. - STAMPA. - 117:2(2003), pp. 121-126. [10.1007/s00414-002-0349-0]
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/43972
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 13
  • ???jsp.display-item.citation.isi??? 11
social impact