In this article some of the actions of amphibian skin peptide Bombesin (BBS) on human gastrointestinal and pancreatic functions are reviewed. BBS causes increases of lower esophageal sphincter pressure, delay of gastric emptying, inhibition of mechanical activity of duodenum and jejunum and gallbladder emptying. BBS also releases in man gastrin and stimulates gastric acid secretion. BBS administration induces release of insulin, glucagon and pancreatic polypeptide from human Islet of Langerhans and causes secretion of pancreatic bicarbonates and enzymes in duodenal juice and release of pancreatic enzymes in blood stream. © 1985.

BOMBESIN EFFECTS ON HUMAN GI FUNCTIONS / DELLE FAVE, Gianfranco; Annibale, Bruno; L., De Magistris; Severi, Carola; R., Bruzzone; M., Puoti; P., Melchiorri; A., Torsoli; V., Erspamer. - In: PEPTIDES. - ISSN 0196-9781. - STAMPA. - 6:3(1985), pp. 113-116. [10.1016/0196-9781(85)90360-2]

BOMBESIN EFFECTS ON HUMAN GI FUNCTIONS

DELLE FAVE, Gianfranco;ANNIBALE, Bruno;SEVERI, Carola;
1985

Abstract

In this article some of the actions of amphibian skin peptide Bombesin (BBS) on human gastrointestinal and pancreatic functions are reviewed. BBS causes increases of lower esophageal sphincter pressure, delay of gastric emptying, inhibition of mechanical activity of duodenum and jejunum and gallbladder emptying. BBS also releases in man gastrin and stimulates gastric acid secretion. BBS administration induces release of insulin, glucagon and pancreatic polypeptide from human Islet of Langerhans and causes secretion of pancreatic bicarbonates and enzymes in duodenal juice and release of pancreatic enzymes in blood stream. © 1985.
1985
bombesin; gastric endocrine secretion; gastric exocrine secretion; gut hormones; motility; pancreatic endocrine secretion; pancreatic exocrine secretion
01 Pubblicazione su rivista::01a Articolo in rivista
BOMBESIN EFFECTS ON HUMAN GI FUNCTIONS / DELLE FAVE, Gianfranco; Annibale, Bruno; L., De Magistris; Severi, Carola; R., Bruzzone; M., Puoti; P., Melchiorri; A., Torsoli; V., Erspamer. - In: PEPTIDES. - ISSN 0196-9781. - STAMPA. - 6:3(1985), pp. 113-116. [10.1016/0196-9781(85)90360-2]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/42690
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