The hormonal responsiveness of plasma membrane-bound enzymes (Na+-K+)-ATPase and adenylate cyclase has been investigated in normal and regenerting rat liver. (Na+-K+)-ATPase basal activity is not affected by surgery and only slightly affected by partial hepatectomy; its response to epinephrine and cyclic AMP is decreased only 15 h after hepatectomy. Adenylate cyclase activity of plasma membranes from untreated animals is stimulated by parathyroid hormone and thyroxine; partial hepatectomy increased basal activity as well as the stimulation exerted by the aforementioned hormones, when glucagon and epinephrine sensitivity is essentially unaltered. © 1975.

Hormone responsiveness of plasma membrane-bound enzymes in normal and regenerating rat liver / S., Leoni; P., Luly; M. T., Mangiantini; S., Spagnuolo; A., Trentalance; Verna, Roberto. - In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. - ISSN 0005-2736. - STAMPA. - 394:2(1975), pp. 317-322.

Hormone responsiveness of plasma membrane-bound enzymes in normal and regenerating rat liver

VERNA, Roberto
1975

Abstract

The hormonal responsiveness of plasma membrane-bound enzymes (Na+-K+)-ATPase and adenylate cyclase has been investigated in normal and regenerting rat liver. (Na+-K+)-ATPase basal activity is not affected by surgery and only slightly affected by partial hepatectomy; its response to epinephrine and cyclic AMP is decreased only 15 h after hepatectomy. Adenylate cyclase activity of plasma membranes from untreated animals is stimulated by parathyroid hormone and thyroxine; partial hepatectomy increased basal activity as well as the stimulation exerted by the aforementioned hormones, when glucagon and epinephrine sensitivity is essentially unaltered. © 1975.
1975
01 Pubblicazione su rivista::01a Articolo in rivista
Hormone responsiveness of plasma membrane-bound enzymes in normal and regenerating rat liver / S., Leoni; P., Luly; M. T., Mangiantini; S., Spagnuolo; A., Trentalance; Verna, Roberto. - In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. - ISSN 0005-2736. - STAMPA. - 394:2(1975), pp. 317-322.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/417280
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