2 patients have been investigated, in which Y chromosome duplication occurred during blastic transformation of chronic myelocytic leukaemia. Comparison of cytogenetic findings and survival data in our cases and in previously reported individuals, suggests preliminary conclusions about the prognostic significance of this aneuploidy. Y chromosome gain does not seem to represent per se an unfavourable event, unless it is associated with additional chromosome change.
Y chromosome duplication: a minor route evolutive pattern in CML / Alimena, Giuliana; Mandelli, Franco; A., Montuoro; R., Gastaldi; B., Dallapiccola. - In: ACTA HAEMATOLOGICA. - ISSN 0001-5792. - 61:6(1979), pp. 310-316.
Y chromosome duplication: a minor route evolutive pattern in CML.
ALIMENA, Giuliana;MANDELLI, Franco;
1979
Abstract
2 patients have been investigated, in which Y chromosome duplication occurred during blastic transformation of chronic myelocytic leukaemia. Comparison of cytogenetic findings and survival data in our cases and in previously reported individuals, suggests preliminary conclusions about the prognostic significance of this aneuploidy. Y chromosome gain does not seem to represent per se an unfavourable event, unless it is associated with additional chromosome change.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
