Spectinomycin displays a dose-dependent neuromuscular blocking activity in vivo. The neuromuscular blockade elicited by spectinomycin is potentiated by d-tubocurarine. Neostigmine methylsulfate is unable to reverse the neuromuscular blocking activity of spectinomycin, whereas calcium chloride counteracts the neuromuscular blockade induced by this antibiotic.
The neuromuscular blocking activity of spectinomycin on the rat sciatic nerve- gastrocnemius muscle preparation / Renna, G; Cagiano, R; Fiore, T; Cuomo, Vincenzo. - In: PHARMACOLOGICAL RESEARCH COMMUNICATIONS. - ISSN 0031-6989. - STAMPA. - 18(5):(1986), pp. 451-457. [10.1016/0031-6989(86)90165-7]
The neuromuscular blocking activity of spectinomycin on the rat sciatic nerve- gastrocnemius muscle preparation
CUOMO, VINCENZO
1986
Abstract
Spectinomycin displays a dose-dependent neuromuscular blocking activity in vivo. The neuromuscular blockade elicited by spectinomycin is potentiated by d-tubocurarine. Neostigmine methylsulfate is unable to reverse the neuromuscular blocking activity of spectinomycin, whereas calcium chloride counteracts the neuromuscular blockade induced by this antibiotic.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.