Food intake is modulated mainly within the hypothalamus, which continuously regulates the energy status of the body by directly sensing the presence of nutrients in the blood stream and by receiving afferent input from the periphery (oronasal, gut, liver, adipose tissue). Also, monoamines and neuropeptides produced in the brain and the gastrointestinal tract during a meal can directly or indirectly activate vagal afferents and mediate many of the nutrients' effects on appetite, gut functions, anabolism, and catabolism. In the hypothalamus, specific neuronal populations transduce these inputs into neuronal responses and, via second order neuronal signaling pathways and efferent output, into behavioral responses. © 2008 European Society for Clinical Nutrition and Metabolism.
Basics in clinical nutrition: Appetite and its control / Michael M., Meguid; Laviano, Alessandro. - 3:6(2008), pp. e272-e274. [10.1016/j.eclnm.2008.06.007]
Basics in clinical nutrition: Appetite and its control
LAVIANO, Alessandro
2008
Abstract
Food intake is modulated mainly within the hypothalamus, which continuously regulates the energy status of the body by directly sensing the presence of nutrients in the blood stream and by receiving afferent input from the periphery (oronasal, gut, liver, adipose tissue). Also, monoamines and neuropeptides produced in the brain and the gastrointestinal tract during a meal can directly or indirectly activate vagal afferents and mediate many of the nutrients' effects on appetite, gut functions, anabolism, and catabolism. In the hypothalamus, specific neuronal populations transduce these inputs into neuronal responses and, via second order neuronal signaling pathways and efferent output, into behavioral responses. © 2008 European Society for Clinical Nutrition and Metabolism.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
