The use of enoxaparin as a replacement drug to standard heparin, for anticoagulation during extracorporeal circulation, in patients with heparin-induced thrombocytopenia, is still very limited. Enoxaparin significantly reduces thrombin formation and activity during cardiopulmonary bypass. The prolonged circulating rate, slow elimination rate and non-total reversion of enoxaparin by protamine can induce important postoperative bleeding. We are describing the first case of cardiac transplantation where enoxaparin was used as a replacement drug to standard heparin. (C) 2000 Elsevier Science B.V. All rights reserved.

Undergoing cardiopulmonary bypass using enoxaparin only during a cardiac transplantation procedure / E., Prifti; M., Bonacchi; M., Leacche; Miraldi, Fabio. - In: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. - ISSN 1010-7940. - 17:6(2000), pp. 760-762. [10.1016/s1010-7940(00)00404-8]

Undergoing cardiopulmonary bypass using enoxaparin only during a cardiac transplantation procedure

MIRALDI, Fabio
2000

Abstract

The use of enoxaparin as a replacement drug to standard heparin, for anticoagulation during extracorporeal circulation, in patients with heparin-induced thrombocytopenia, is still very limited. Enoxaparin significantly reduces thrombin formation and activity during cardiopulmonary bypass. The prolonged circulating rate, slow elimination rate and non-total reversion of enoxaparin by protamine can induce important postoperative bleeding. We are describing the first case of cardiac transplantation where enoxaparin was used as a replacement drug to standard heparin. (C) 2000 Elsevier Science B.V. All rights reserved.
2000
cardiac transplantation; enoxaparin; heparin-induced thrombocytopenia
01 Pubblicazione su rivista::01a Articolo in rivista
Undergoing cardiopulmonary bypass using enoxaparin only during a cardiac transplantation procedure / E., Prifti; M., Bonacchi; M., Leacche; Miraldi, Fabio. - In: EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. - ISSN 1010-7940. - 17:6(2000), pp. 760-762. [10.1016/s1010-7940(00)00404-8]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/39860
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