The particular period of exposure to psychotropic drugs plays a critical role in producing behavioural abnormalities in rodents. The administration of various neuroleptic, antidepressant and anti-anxiety agents prenatally or to neonatal animals can lead to short- and long-term behavioural changes that are not obtained by treating adult animals,Vincenzo Cuomo explains that these behavioural changes, which occur in the absence of overt signs of neurotoxicity, may be the consequence of subtle alterations in physiological and biochemical aspects of the CNS.
Perinatal neurotoxicology of psychotropic drugs / Cuomo, Vincenzo. - In: TRENDS IN PHARMACOLOGICAL SCIENCES. - ISSN 0165-6147. - STAMPA. - 8:(1987), pp. 346-350. [10.1016/0165-6147(87)90144-1]
Perinatal neurotoxicology of psychotropic drugs
CUOMO, VINCENZO
1987
Abstract
The particular period of exposure to psychotropic drugs plays a critical role in producing behavioural abnormalities in rodents. The administration of various neuroleptic, antidepressant and anti-anxiety agents prenatally or to neonatal animals can lead to short- and long-term behavioural changes that are not obtained by treating adult animals,Vincenzo Cuomo explains that these behavioural changes, which occur in the absence of overt signs of neurotoxicity, may be the consequence of subtle alterations in physiological and biochemical aspects of the CNS.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.