The purpose of our study was to evaluate the accuracy of multidetector CT (MDCT) using a high-resolution protocol in the preoperative assessment of patients with renal cell carcinoma who are possible candidates for nephron-sparing surgery.Forty patients with suspected renal cell carcinoma underwent MDCT. Contrast-enhanced acquisitions were obtained during arterial, nephrographic, and urographic phases using a thin-slice protocol. One-millimeter-thick source images were evaluated by two observers on a dedicated workstation for the identification and characterization of the tumor, presence of a pseudocapsule or invasion of perirenal fat, involvement of adrenal glands or surrounding tissues, presence of satellite lesions within Gerota's fascia, infiltration of renal vein and inferior vena cava, involvement of lymph nodes, and presence of distant metastases. Imaging findings were compared with surgical specimens using criteria from the Robson and TNM classification systems.The presence and size of all lesions were correctly shown in all patients. In evaluating Robson stage I of renal cell carcinoma, we were able to diagnose fat infiltration on 1-mm scans with 96\% sensitivity, 93\% specificity, and 95\% accuracy; the positive and negative predictive values were, respectively, 100\% and 93\%. One hundred percent accuracy was achieved in staging high-grade lesions.High-resolution MDCT is accurate in the preoperative evaluation of patients with renal cell carcinoma.

High-resolution multidetector CT in the preoperative evaluation of patients with renal cell carcinoma / Catalano, Carlo; F., Fraioli; Laghi, Andrea; Napoli, Alessandro; Pediconi, Federica; M., Danti; P., Nardis; Passariello, Roberto. - In: AMERICAN JOURNAL OF ROENTGENOLOGY. - ISSN 0361-803X. - STAMPA. - 180:(2003), pp. 1271-1277.

High-resolution multidetector CT in the preoperative evaluation of patients with renal cell carcinoma

CATALANO, Carlo;LAGHI, ANDREA;NAPOLI, ALESSANDRO;PEDICONI, FEDERICA;PASSARIELLO, Roberto
2003

Abstract

The purpose of our study was to evaluate the accuracy of multidetector CT (MDCT) using a high-resolution protocol in the preoperative assessment of patients with renal cell carcinoma who are possible candidates for nephron-sparing surgery.Forty patients with suspected renal cell carcinoma underwent MDCT. Contrast-enhanced acquisitions were obtained during arterial, nephrographic, and urographic phases using a thin-slice protocol. One-millimeter-thick source images were evaluated by two observers on a dedicated workstation for the identification and characterization of the tumor, presence of a pseudocapsule or invasion of perirenal fat, involvement of adrenal glands or surrounding tissues, presence of satellite lesions within Gerota's fascia, infiltration of renal vein and inferior vena cava, involvement of lymph nodes, and presence of distant metastases. Imaging findings were compared with surgical specimens using criteria from the Robson and TNM classification systems.The presence and size of all lesions were correctly shown in all patients. In evaluating Robson stage I of renal cell carcinoma, we were able to diagnose fat infiltration on 1-mm scans with 96\% sensitivity, 93\% specificity, and 95\% accuracy; the positive and negative predictive values were, respectively, 100\% and 93\%. One hundred percent accuracy was achieved in staging high-grade lesions.High-resolution MDCT is accurate in the preoperative evaluation of patients with renal cell carcinoma.
2003
Preoperative Care; Humans; Female; Carcinoma: Renal Cell; Kidney Neoplasms; Tomography: X-Ray Computed; Aged; Middle Aged; Reproducibility of Results; Adult; Male
01 Pubblicazione su rivista::01a Articolo in rivista
High-resolution multidetector CT in the preoperative evaluation of patients with renal cell carcinoma / Catalano, Carlo; F., Fraioli; Laghi, Andrea; Napoli, Alessandro; Pediconi, Federica; M., Danti; P., Nardis; Passariello, Roberto. - In: AMERICAN JOURNAL OF ROENTGENOLOGY. - ISSN 0361-803X. - STAMPA. - 180:(2003), pp. 1271-1277.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/386987
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