A theoretical model of the sequence dependent superstructures of DNA is proposed on the basis of conformational energy calculations. The model appears to contain the basic physical features for translating the deterministic fluctuations of DNA bases sequences in superstructure elements. The general superstructural features, found in many examples of DNA biologically significative tracts we have investigated, suggest that large scale dynamics, as firstly shown by Careri in the case of enzymes, could be of relevance also in the case of DNA.

A theoretical model of the sequence dependent superstructures of DNA / P., De Santis; G., Gallo; A., Palleschi; M., Savino; Scipioni, Anita. - In: JOURNAL OF MOLECULAR LIQUIDS. - ISSN 0167-7322. - STAMPA. - 41:(1989), pp. 291-304. [10.1016/0167-7322(89)80085-6]

A theoretical model of the sequence dependent superstructures of DNA

SCIPIONI, Anita
1989

Abstract

A theoretical model of the sequence dependent superstructures of DNA is proposed on the basis of conformational energy calculations. The model appears to contain the basic physical features for translating the deterministic fluctuations of DNA bases sequences in superstructure elements. The general superstructural features, found in many examples of DNA biologically significative tracts we have investigated, suggest that large scale dynamics, as firstly shown by Careri in the case of enzymes, could be of relevance also in the case of DNA.
1989
DNA superstructures; electrophoretic retardation of curved DNAs; theoretical model for the prediction of DNA curvature
01 Pubblicazione su rivista::01a Articolo in rivista
A theoretical model of the sequence dependent superstructures of DNA / P., De Santis; G., Gallo; A., Palleschi; M., Savino; Scipioni, Anita. - In: JOURNAL OF MOLECULAR LIQUIDS. - ISSN 0167-7322. - STAMPA. - 41:(1989), pp. 291-304. [10.1016/0167-7322(89)80085-6]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/386466
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