Clinical practice and studies (1-3) have shown that individual differences in sensitivity to colour exist. We investigated if the role of colour might be helpful in genetic research. In 11 photosensitive patients and 11 control patients, including first-degree family members without a PPR, standardised IPS has been performed with a Grass PS 33: photosensitivity ranges were determined in the three eye conditions for white light and coloured light (commercially available filters: blue, green, yellow, orange and red) presented in a random order. In this way, a ranking order in sensitivity ranges per patient per light stimulus could be established. Only those patients, who responded to white light, proved to be sensitive to coloured light. Although overall orange, yellow and red flickering light proved to be the most provocative, clear inter and intra-individual differences in type of EEG responses and ranges were found. The spectrum of sensitivity to various colours was in general diverse with similarities in a father and daughter. Further family studies are warranted.
Role of colour in Photosensitive Epilepsy: is it possible to detect new Endo-phenotypes? / Laura, Cantonetti; Buttinelli, Carla; GIANCARLO ROSSI FEDELE MATRI, ; Marta, Piccioli; Caporro, Matteo; Ferraldeschi, Michela; Paolo, Tisei; Parisi, Pasquale; Anna, Luchetti; Laura, Conti; Caterina, Cerminara; Riccardo, Terenzi; DOROTHÉE KASTELEIJN NOLST TRENITÉ,. - 138(2008), pp. 179-180. (Intervento presentato al convegno American Epilepsy Society (AES). tenutosi a Seattle; United States nel December 5-9,2008).
Role of colour in Photosensitive Epilepsy: is it possible to detect new Endo-phenotypes?
BUTTINELLI, Carla;CAPORRO, MATTEO;MICHELA FERRALDESCHI;PARISI, Pasquale;
2008
Abstract
Clinical practice and studies (1-3) have shown that individual differences in sensitivity to colour exist. We investigated if the role of colour might be helpful in genetic research. In 11 photosensitive patients and 11 control patients, including first-degree family members without a PPR, standardised IPS has been performed with a Grass PS 33: photosensitivity ranges were determined in the three eye conditions for white light and coloured light (commercially available filters: blue, green, yellow, orange and red) presented in a random order. In this way, a ranking order in sensitivity ranges per patient per light stimulus could be established. Only those patients, who responded to white light, proved to be sensitive to coloured light. Although overall orange, yellow and red flickering light proved to be the most provocative, clear inter and intra-individual differences in type of EEG responses and ranges were found. The spectrum of sensitivity to various colours was in general diverse with similarities in a father and daughter. Further family studies are warranted.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
