An exogenous electromagnetic field can be thought of as inducing a perturbation on membrane potential, thus acting as an input of neuronal encoding process. To investigate possible field-induced effects over neuronal response, a double compartment model is set-up, displaying a variety of firing and bursting patterns related to the coupling between fast and slow dynamics ionic channels. Channel noise, which has been shown to play a significant role in neuronal processing, is accurately modeled in both fast and slow compartments, thus resulting in a good qualitative agreement with experimental data in both temporal responses and in firing and bursting statistics. In such conditions, the effects of a field-induced electromagnetic perturbation are studied on neuronal output patterns and statistical features
Modeling Biological Noise in Firing and Bursting Neurons in the Presence of an Electromagnetic Field / Gianni', M; Maggio, F; Liberti, Micaela; Paffi, Alessandra; Apollonio, Francesca; D'Inzeo, Guglielmo. - STAMPA. - (2005), pp. 237-240. (Intervento presentato al convegno 2nd International IEEE EMBS Conference on Neural Engineering, 2005 tenutosi a Washington D.C., USA / Arlington, USA nel 16-19 March 2005) [10.1109/CNE.2005.1419600].
Modeling Biological Noise in Firing and Bursting Neurons in the Presence of an Electromagnetic Field
LIBERTI, Micaela;PAFFI, ALESSANDRA;APOLLONIO, Francesca;D'INZEO, Guglielmo
2005
Abstract
An exogenous electromagnetic field can be thought of as inducing a perturbation on membrane potential, thus acting as an input of neuronal encoding process. To investigate possible field-induced effects over neuronal response, a double compartment model is set-up, displaying a variety of firing and bursting patterns related to the coupling between fast and slow dynamics ionic channels. Channel noise, which has been shown to play a significant role in neuronal processing, is accurately modeled in both fast and slow compartments, thus resulting in a good qualitative agreement with experimental data in both temporal responses and in firing and bursting statistics. In such conditions, the effects of a field-induced electromagnetic perturbation are studied on neuronal output patterns and statistical featuresI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.