Bv8, a protein from skin secretions of Bombina variegata, reacts with receptors present in mammalian brain and intestine (Mollay et al, (1999) Eur, J, Pharmacol, 374, 189-196), As deduced from cloned cDNAs, the murine and human Bv8 homologues hare identical amino-terminal sequences and also contain 10 cysteines, From mouse testes, two forms of Bv8 mRNA have been characterized, of which one contains an additional exon which codes for 21 mostly basic amino acids. The mouse Bv8 gene is most active in mid-late pachytene spermatocytes. In mouse testes, Bv8 mRNA can first be detected at the end of the second week post partum, (C) 1999 Federation of European Biochemical Societies.

The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes / Christian, Wechselberger; Puglisi, Rossella; Edwin, Engel; Günter, Lepperdinger; Boitani, Carla; Günther, Kreil. - In: FEBS LETTERS. - ISSN 0014-5793. - STAMPA. - 462:1-2(1999), pp. 177-181. [10.1016/s0014-5793(99)01473-8]

The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes

PUGLISI, Rossella;BOITANI, Carla;
1999

Abstract

Bv8, a protein from skin secretions of Bombina variegata, reacts with receptors present in mammalian brain and intestine (Mollay et al, (1999) Eur, J, Pharmacol, 374, 189-196), As deduced from cloned cDNAs, the murine and human Bv8 homologues hare identical amino-terminal sequences and also contain 10 cysteines, From mouse testes, two forms of Bv8 mRNA have been characterized, of which one contains an additional exon which codes for 21 mostly basic amino acids. The mouse Bv8 gene is most active in mid-late pachytene spermatocytes. In mouse testes, Bv8 mRNA can first be detected at the end of the second week post partum, (C) 1999 Federation of European Biochemical Societies.
1999
hyperalgesia; orphan ligand; spermatogenesis
01 Pubblicazione su rivista::01a Articolo in rivista
The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes / Christian, Wechselberger; Puglisi, Rossella; Edwin, Engel; Günter, Lepperdinger; Boitani, Carla; Günther, Kreil. - In: FEBS LETTERS. - ISSN 0014-5793. - STAMPA. - 462:1-2(1999), pp. 177-181. [10.1016/s0014-5793(99)01473-8]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/361658
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