Although human Y chromosomes belonging to haplogroup R1b are quite rare in Africa, being found mainly in Asia and Europe, a group of chromosomes within the paragroup R-P25* are found concentrated in the central-western part of the African continent, where they can be detected at frequencies as high as 95%. Phylogenetic evidence and coalescence time estimates suggest that R-P25* chromosomes (or their phylogenetic ancestor) may have been carried to Africa by an Asia-to-Africa back migration in prehistoric times. Here, we describe six new mutations that define the relationships among the African R-P25* Y chromosomes and between these African chromosomes and earlier reported R-P25 Eurasian sub-lineages. The incorporation of these new mutations into a phylogeny of the R1b haplogroup led to the identification of a new clade (R1b1a or R-V88) encompassing all the African R-P25* and about half of the few European/west Asian R-P25* chromosomes. A worldwide phylogeographic analysis of the R1b haplogroup provided strong support to the Asia-to-Africa back-migration hypothesis. The analysis of the distribution of the R-V88 haplogroup in 41800 males from 69 African populations revealed a striking genetic contiguity between the Chadic-speaking peoples from the central Sahel and several other Afroasiatic-speaking groups from North Africa. The R-V88 coalescence time was estimated at 9200-5600 kya, in the early mid Holocene. We suggest that R-V88 is a paternal genetic record of the proposed mid-Holocene migration of proto-Chadic Afroasiatic speakers through the Central Sahara into the Lake Chad Basin, and geomorphological evidence is consistent with this view.

Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages / Cruciani, Fulvio; Trombetta, Beniamino; Daniele, Sellitto; Massaia, Andrea; DESTRO-BISOL, Giovanni; Elizabeth, Watson; E. B., Colomb; Eliane Beraud, Colomb; Jean Michel, Dugoujon; Pedro, Moral; Scozzari, Rosaria. - In: EUROPEAN JOURNAL OF HUMAN GENETICS. - ISSN 1018-4813. - 18:7(2010), pp. 800-807. [10.1038/ejhg.2009.231]

Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages

CRUCIANI, Fulvio;TROMBETTA, BENIAMINO;MASSAIA, ANDREA;DESTRO-BISOL, Giovanni;SCOZZARI, Rosaria
2010

Abstract

Although human Y chromosomes belonging to haplogroup R1b are quite rare in Africa, being found mainly in Asia and Europe, a group of chromosomes within the paragroup R-P25* are found concentrated in the central-western part of the African continent, where they can be detected at frequencies as high as 95%. Phylogenetic evidence and coalescence time estimates suggest that R-P25* chromosomes (or their phylogenetic ancestor) may have been carried to Africa by an Asia-to-Africa back migration in prehistoric times. Here, we describe six new mutations that define the relationships among the African R-P25* Y chromosomes and between these African chromosomes and earlier reported R-P25 Eurasian sub-lineages. The incorporation of these new mutations into a phylogeny of the R1b haplogroup led to the identification of a new clade (R1b1a or R-V88) encompassing all the African R-P25* and about half of the few European/west Asian R-P25* chromosomes. A worldwide phylogeographic analysis of the R1b haplogroup provided strong support to the Asia-to-Africa back-migration hypothesis. The analysis of the distribution of the R-V88 haplogroup in 41800 males from 69 African populations revealed a striking genetic contiguity between the Chadic-speaking peoples from the central Sahel and several other Afroasiatic-speaking groups from North Africa. The R-V88 coalescence time was estimated at 9200-5600 kya, in the early mid Holocene. We suggest that R-V88 is a paternal genetic record of the proposed mid-Holocene migration of proto-Chadic Afroasiatic speakers through the Central Sahara into the Lake Chad Basin, and geomorphological evidence is consistent with this view.
2010
human migrations; chadic-speaking populations; y chromosome haplogroups; holocene; africa
01 Pubblicazione su rivista::01a Articolo in rivista
Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages / Cruciani, Fulvio; Trombetta, Beniamino; Daniele, Sellitto; Massaia, Andrea; DESTRO-BISOL, Giovanni; Elizabeth, Watson; E. B., Colomb; Eliane Beraud, Colomb; Jean Michel, Dugoujon; Pedro, Moral; Scozzari, Rosaria. - In: EUROPEAN JOURNAL OF HUMAN GENETICS. - ISSN 1018-4813. - 18:7(2010), pp. 800-807. [10.1038/ejhg.2009.231]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/359921
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