The heart has traditionally been considered a terminally differentiated organ. In the past 10 years, though, this paradigm has been challenged and proved questionable, starting from the evidence of cycling myocytes in the adult heart, both in physiological and in pathological conditions. In addition, the discovery and isolation of cells from the adult heart with progenitor-like and stem-like features has started a new field of research. These topics are reviewed in this chapter.
Evidence for the Existence of Resident Cardiac Stem Cells / Chimenti, Isotta; Gaetani, Roberto; Barile, Lucio; Forte, Elvira; Ionta, Vittoria; Angelini, Francesco; Messina, Elisa; Giacomello, Alessandro. - STAMPA. - (2011), pp. 131-147. [10.1007/978-1-61779-021-8_9].
Evidence for the Existence of Resident Cardiac Stem Cells
CHIMENTI, ISOTTA;GAETANI, ROBERTO;BARILE, Lucio;FORTE, ELVIRA;IONTA, VITTORIA;ANGELINI, FRANCESCO;MESSINA, ELISA;GIACOMELLO, Alessandro
2011
Abstract
The heart has traditionally been considered a terminally differentiated organ. In the past 10 years, though, this paradigm has been challenged and proved questionable, starting from the evidence of cycling myocytes in the adult heart, both in physiological and in pathological conditions. In addition, the discovery and isolation of cells from the adult heart with progenitor-like and stem-like features has started a new field of research. These topics are reviewed in this chapter.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
