The direct separation of beta-aminoester enantiomers by HPLC on synthetic chiral stationary phases based on a pi-acidic derivative of trans 1,2-diaminocyclohexane as selector is described. The application of different columns containing the stationary phase with opposite configurations and in the racemic form to the determination of enantiomeric excess in chemically impure samples is demonstrated.
Direct HPLC Separation of beta-aminoester enantiomers on a totally synthetic chiral stationary phases / Gasparrini, Francesco; D'Acquarica, Ilaria; Villani, Claudio; C., Cimarelli; G., Palmieri. - In: BIOMEDICAL CHROMATOGRAPHY. - ISSN 0269-3879. - STAMPA. - 11:(1997), pp. 317-320. [10.1002/(SICI)1099-0801(199709)11:5<317::AID-BMC706>3.0.CO;2-M]
Direct HPLC Separation of beta-aminoester enantiomers on a totally synthetic chiral stationary phases
GASPARRINI, Francesco;D'ACQUARICA, Ilaria;VILLANI, Claudio;
1997
Abstract
The direct separation of beta-aminoester enantiomers by HPLC on synthetic chiral stationary phases based on a pi-acidic derivative of trans 1,2-diaminocyclohexane as selector is described. The application of different columns containing the stationary phase with opposite configurations and in the racemic form to the determination of enantiomeric excess in chemically impure samples is demonstrated.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
