Viburnum species are used in folk medicine because of their diuretic, antispasmodic and sedative properties. In this study the sedative and antispasmodic activities of a total extract from Viburnum tinus and its major compounds (viburtinoside I, II/III) were evaluated on spontaneous locomotor activity in mice and on isolated rabbit jejunum. V. tinus and its components reduced spontaneous activity in mice, viburtinoside I being more potent than viburtinoside II/III. The isolated compounds also had spasmolytic action in vitro, viburtinosides II/III being more potent than viburtinoside I. (C) 1998 John Wiley & Sons, Ltd.
Sedative and spasmolytic effects of Viburnum tinus L. and its major pure compounds / M. F., Cometa; Mazzanti, Gabriela; Tomassini, Lamberto. - In: PHYTOTHERAPY RESEARCH. - ISSN 0951-418X. - STAMPA. - 12:1(1998), pp. S89-S91. (Intervento presentato al convegno 2nd International Symposium on Natural Drugs tenutosi a MELFI, ITALY nel SEP 28-OCT 01, 1997) [10.1002/(sici)1099-1573(1998)12:1+<s89::aid-ptr260>3.0.co;2-t].
Sedative and spasmolytic effects of Viburnum tinus L. and its major pure compounds
MAZZANTI, Gabriela;TOMASSINI, Lamberto
1998
Abstract
Viburnum species are used in folk medicine because of their diuretic, antispasmodic and sedative properties. In this study the sedative and antispasmodic activities of a total extract from Viburnum tinus and its major compounds (viburtinoside I, II/III) were evaluated on spontaneous locomotor activity in mice and on isolated rabbit jejunum. V. tinus and its components reduced spontaneous activity in mice, viburtinoside I being more potent than viburtinoside II/III. The isolated compounds also had spasmolytic action in vitro, viburtinosides II/III being more potent than viburtinoside I. (C) 1998 John Wiley & Sons, Ltd.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.