A large mass in the right orbit, causing proptosis, ptosis of the right upper eyelid, and limitation to eye movements, was surgically removed from a 51-year-old woman suffering from Paget's bone disease (PBD). Histologically, a giant cell tumor of the bone (osteoclastoma) was diagnosed. No bony involvement was apparent either operatively, microscopically, or on preoperative computed tomographic scans. The neoplasm has not recurred in a 3-year follow-up. In addition to the fact that osteoclastoma complicating PBD is rare, the extraskeletal origin of the tumor is a matter of interest and can be tentatively explained by an unusually powerful systemic stimulus acting on circulating osteoclast precursors. Copyright © 2000 by W.B. Saunders Company.
Orbital osteoclastoma of apparent extraskeletal origin in a pagetic patient: A case report / Pecorella, Irene; Ciardi, Antonio; G., Amadeo; A., Baiocchini; A., Marasco; DI TONDO, Ugo. - In: HUMAN PATHOLOGY. - ISSN 0046-8177. - STAMPA. - 31:12(2000), pp. 1527-1531. [10.1053/hupa.2000.20411]
Orbital osteoclastoma of apparent extraskeletal origin in a pagetic patient: A case report
PECORELLA, Irene;CIARDI, Antonio;DI TONDO, Ugo
2000
Abstract
A large mass in the right orbit, causing proptosis, ptosis of the right upper eyelid, and limitation to eye movements, was surgically removed from a 51-year-old woman suffering from Paget's bone disease (PBD). Histologically, a giant cell tumor of the bone (osteoclastoma) was diagnosed. No bony involvement was apparent either operatively, microscopically, or on preoperative computed tomographic scans. The neoplasm has not recurred in a 3-year follow-up. In addition to the fact that osteoclastoma complicating PBD is rare, the extraskeletal origin of the tumor is a matter of interest and can be tentatively explained by an unusually powerful systemic stimulus acting on circulating osteoclast precursors. Copyright © 2000 by W.B. Saunders Company.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.