To detect signs of axonal damage in MS, the authors investigated the occurrence in EMG of motor unit action potentials with satellite potentials (SP-MUAP) in the upper limb muscles in 10 consecutive patients with MS with cervical spinal cord demyelinating lesions and 10 control subjects. Subjects' SP-MUAP rate was 0 to 2.5% (median 0%) in the control group, and 0 to 17.5% (median 7.5%) in the MS group (p < 0.01). Motor unit remodeling secondary to axonal transection of spinal motor neurons traversing cervical demyelinating lesions may be hypothesized
Satellite potentials on EMG: neurophysiologic evidence of axonal transection in MS? / Antonini, Giovanni; Morino, S.; Giubilei, Franco; Paolillo, A.; Ceschin, V.; Gragnani, F.; Bucci, Elisabetta; Pozzilli, Carlo. - In: NEUROLOGY. - ISSN 0028-3878. - STAMPA. - 57:(2001), pp. 1126-1128.
Satellite potentials on EMG: neurophysiologic evidence of axonal transection in MS?
ANTONINI, Giovanni;GIUBILEI, Franco;BUCCI, ELISABETTA;POZZILLI, Carlo
2001
Abstract
To detect signs of axonal damage in MS, the authors investigated the occurrence in EMG of motor unit action potentials with satellite potentials (SP-MUAP) in the upper limb muscles in 10 consecutive patients with MS with cervical spinal cord demyelinating lesions and 10 control subjects. Subjects' SP-MUAP rate was 0 to 2.5% (median 0%) in the control group, and 0 to 17.5% (median 7.5%) in the MS group (p < 0.01). Motor unit remodeling secondary to axonal transection of spinal motor neurons traversing cervical demyelinating lesions may be hypothesizedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
