An overview is presented of the exptl. results obtained by our group in the design, realization, and applications of high-performance liq. chromatog. (HPLC) enantioselective stationary phases based on surface-linked macrocyclic receptors. Macrocyclic synthetic receptors and macrocyclic glycopeptide receptors have been grafted on silica particles, and the resulting chiral stationary phases are used to monitor differential assocns. of the enantiomers of selected chiral guests with the immobilized hosts. Practical implications of the chiral phases in enantioselective anal. and in the study of recognition events are highlighted.
Natural and totally synthetic receptors in the innovative design of HPLC chiral stationary phases / Gasparrini, Francesco; D'Acquarica, Ilaria; Misiti, Domenico; Pierini, Marco; Villani, Claudio. - In: PURE AND APPLIED CHEMISTRY. - ISSN 0033-4545. - STAMPA. - 75:(2003), pp. 407-412. [10.1351/pac200375020407]
Natural and totally synthetic receptors in the innovative design of HPLC chiral stationary phases
GASPARRINI, Francesco;D'ACQUARICA, Ilaria;MISITI, Domenico;PIERINI, MARCO;VILLANI, Claudio
2003
Abstract
An overview is presented of the exptl. results obtained by our group in the design, realization, and applications of high-performance liq. chromatog. (HPLC) enantioselective stationary phases based on surface-linked macrocyclic receptors. Macrocyclic synthetic receptors and macrocyclic glycopeptide receptors have been grafted on silica particles, and the resulting chiral stationary phases are used to monitor differential assocns. of the enantiomers of selected chiral guests with the immobilized hosts. Practical implications of the chiral phases in enantioselective anal. and in the study of recognition events are highlighted.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
