Background: Sebaceous carcinoma is an unusual, aggressive, malignant tumor derived from the epithelium of sebaceous glands. It may arise in ocular or extra-ocular sites and is often evident as an ulcerated or non-ulcerated cystic nodule measuring up to 8 cm in diameter. A significant number of extra-ocular sebaceous carcinomas have been associated with metastases and high mortality rate. Methods and Results: We reviewed the literature in the context of our report of a 68-year-old woman who had a morpheaform plaque of the upper lip of 15 years duration, extending into the left naso-genal groove, which histologically also showed marked stromal fibrosis. Three years after excision, there were no signs of recurrence or metastases. Conclusions: This patient is unusual in clinical and histologic pattern, as a morpheaform appearance has only been described previously in only one sebaceous carcinoma. In addition, no metastatic disease 15 years after tumor onset is a fortunate and remarkable feature.

Morpheaform extra-ocular sebaceous carcinoma / Cantoresi, Franca; Innocenzi, Daniele; A., Balzani; F., Lupi; C., Panetta; Skroza, Nevena; R. A., Schwartz; Calvieri, Stefano. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 92:4(2005), pp. 344-346. [10.1002/jso.20383]

Morpheaform extra-ocular sebaceous carcinoma

CANTORESI, Franca;INNOCENZI, Daniele;SKROZA, Nevena;CALVIERI, Stefano
2005

Abstract

Background: Sebaceous carcinoma is an unusual, aggressive, malignant tumor derived from the epithelium of sebaceous glands. It may arise in ocular or extra-ocular sites and is often evident as an ulcerated or non-ulcerated cystic nodule measuring up to 8 cm in diameter. A significant number of extra-ocular sebaceous carcinomas have been associated with metastases and high mortality rate. Methods and Results: We reviewed the literature in the context of our report of a 68-year-old woman who had a morpheaform plaque of the upper lip of 15 years duration, extending into the left naso-genal groove, which histologically also showed marked stromal fibrosis. Three years after excision, there were no signs of recurrence or metastases. Conclusions: This patient is unusual in clinical and histologic pattern, as a morpheaform appearance has only been described previously in only one sebaceous carcinoma. In addition, no metastatic disease 15 years after tumor onset is a fortunate and remarkable feature.
2005
adnexal carcinoma; basal cell carcinoma; morphea; sclerosis neoplasm; sebaceous carcinoma
01 Pubblicazione su rivista::01a Articolo in rivista
Morpheaform extra-ocular sebaceous carcinoma / Cantoresi, Franca; Innocenzi, Daniele; A., Balzani; F., Lupi; C., Panetta; Skroza, Nevena; R. A., Schwartz; Calvieri, Stefano. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 92:4(2005), pp. 344-346. [10.1002/jso.20383]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/123243
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