An amidic derivative of a carboxymethylcellulose-based hydrogel was obtained and characterized in terms of amidation degree. NMR studies and FT-IR imaging spectroscopy demonstrated that the reaction allowed a polymer to be obtained that was characterized by a regular distribution of amidic groups along the polysaccharide chains. Through this regularity, a homogenous three-dimensional scaffold was obtained, which maintained the thixotropic property of the linear polysaccharide. © 2007 Elsevier Ltd. All rights reserved.
The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: structural and rheological characterization / Gemma, Leone; Delfini, Maurizio; DI COCCO, Maria Enrica; Anna, Borioni; Rolando, Barbucci. - In: CARBOHYDRATE RESEARCH. - ISSN 0008-6215. - STAMPA. - 343:2(2008), pp. 317-327. [10.1016/j.carres.2007.10.017]
The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: structural and rheological characterization
DELFINI, Maurizio;DI COCCO, Maria Enrica;
2008
Abstract
An amidic derivative of a carboxymethylcellulose-based hydrogel was obtained and characterized in terms of amidation degree. NMR studies and FT-IR imaging spectroscopy demonstrated that the reaction allowed a polymer to be obtained that was characterized by a regular distribution of amidic groups along the polysaccharide chains. Through this regularity, a homogenous three-dimensional scaffold was obtained, which maintained the thixotropic property of the linear polysaccharide. © 2007 Elsevier Ltd. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
