Aims: Many previous researches showed clinical benefits, effects on inflammatory mediators and pain, immune system, hormones and on the diencephalic-pituitary-adrenal axis. Our study evalues the efficacy of mud-bath therapy with mineral water from the Sillene Spring at Italy's Chianciano Spa in patients with osteoarthritis of the knee. Materials and Methods.: In study we compared: physical examination of the knee joint, visual analogue scale (VAS) assessment of pain, and Lequesne Algo-functional Index. Tests were performed in 61 patients divided into 2 groups. The group A underwent three full cycles of mud-bath therapy over 1 year's time, the group B did not. An observational longitudinal study was also conducted on the patients of group A, before and after completion of the treatment protocol. Statistical analyses were based on use of Pearson's χ2 test, Student's t tests for paired and unpaired data. Results: The percentage of patients with no symptoms or mild symptoms was higher in group A than in group B (differences were highly significant); the mean value of VAS and the overall Lequesne indexes mean score reported in group A was significantly lower than that reported in group B. The same we observed comparing the clinical conditions of group A patients before and after mud-bath therapy. No adverse effects were observed in any of the patients in group A. Conclusions: The mud-bath therapy at Chianciano Spa significantly improves the clinical conditions of patients with knee osteoarthritis and significantly reduces the frequency and severity of symptoms and the disability they cause.

Efficacy of mud-bath therapy with mineral water from the Sillene spring at Italy's Chianciano Spa for osteoarthritis of the knee: A clinical statistical study [Efficacia della fangobalneoterapia con acqua minerale sillene (terme di chianciano, Italia) nell'osteoartrosi del ginocchio: Uno studio clinico-statistico] / Fraioli, Antonio; A., Serio; Mennuni, Gioacchino; Ceccarelli, Fulvia; Petraccia, Luisa; J., Campanella; Fontana, Mario; Nocchi, Silvia; G., Tanzi; Grassi, Marcello; Valesini, Guido. - In: LA CLINICA TERAPEUTICA. - ISSN 0009-9074. - ELETTRONICO. - 160:6(2009), pp. e63-e74.

Efficacy of mud-bath therapy with mineral water from the Sillene spring at Italy's Chianciano Spa for osteoarthritis of the knee: A clinical statistical study [Efficacia della fangobalneoterapia con acqua minerale sillene (terme di chianciano, Italia) nell'osteoartrosi del ginocchio: Uno studio clinico-statistico]

FRAIOLI, Antonio;MENNUNI, Gioacchino;CECCARELLI, FULVIA;PETRACCIA, LUISA;FONTANA, Mario;NOCCHI, Silvia;GRASSI, MARCELLO;VALESINI, Guido
2009

Abstract

Aims: Many previous researches showed clinical benefits, effects on inflammatory mediators and pain, immune system, hormones and on the diencephalic-pituitary-adrenal axis. Our study evalues the efficacy of mud-bath therapy with mineral water from the Sillene Spring at Italy's Chianciano Spa in patients with osteoarthritis of the knee. Materials and Methods.: In study we compared: physical examination of the knee joint, visual analogue scale (VAS) assessment of pain, and Lequesne Algo-functional Index. Tests were performed in 61 patients divided into 2 groups. The group A underwent three full cycles of mud-bath therapy over 1 year's time, the group B did not. An observational longitudinal study was also conducted on the patients of group A, before and after completion of the treatment protocol. Statistical analyses were based on use of Pearson's χ2 test, Student's t tests for paired and unpaired data. Results: The percentage of patients with no symptoms or mild symptoms was higher in group A than in group B (differences were highly significant); the mean value of VAS and the overall Lequesne indexes mean score reported in group A was significantly lower than that reported in group B. The same we observed comparing the clinical conditions of group A patients before and after mud-bath therapy. No adverse effects were observed in any of the patients in group A. Conclusions: The mud-bath therapy at Chianciano Spa significantly improves the clinical conditions of patients with knee osteoarthritis and significantly reduces the frequency and severity of symptoms and the disability they cause.
2009
mud-bath therapy; knee osteoartrhitis; spa therapy; osteoarthritis; knee osteoarthritis
01 Pubblicazione su rivista::01a Articolo in rivista
Efficacy of mud-bath therapy with mineral water from the Sillene spring at Italy's Chianciano Spa for osteoarthritis of the knee: A clinical statistical study [Efficacia della fangobalneoterapia con acqua minerale sillene (terme di chianciano, Italia) nell'osteoartrosi del ginocchio: Uno studio clinico-statistico] / Fraioli, Antonio; A., Serio; Mennuni, Gioacchino; Ceccarelli, Fulvia; Petraccia, Luisa; J., Campanella; Fontana, Mario; Nocchi, Silvia; G., Tanzi; Grassi, Marcello; Valesini, Guido. - In: LA CLINICA TERAPEUTICA. - ISSN 0009-9074. - ELETTRONICO. - 160:6(2009), pp. e63-e74.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/229026
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