Novel core–shell magnetic nanocomposites for drug targeting of anticancer drugs were developed by a reverse emulsion process. Two different nanoparticle coatings (albumin and polyethylene oxide) were investigated to elucidate their possible role in controlling drug adsorption and release of methotrexate, used as model anticancer drug. The obtained results evidenced as these formulations may be potentially employed as effective carriers for drug targeting.
Novel manganese-ferrite nanocomposites for targeted delivery of anticancer drugs / Francolini, Iolanda; Palombo, M.; Casini, G.; D'Ilario, Lucio; Martinelli, Andrea; Rinaldelli, V.; Piozzi, Antonella. - In: JOURNAL OF CONTROLLED RELEASE. - ISSN 0168-3659. - STAMPA. - 148:1(2010), pp. 57-59. [10.1016/j.jconrel.2010.07.021]
Novel manganese-ferrite nanocomposites for targeted delivery of anticancer drugs.
Francolini, Iolanda
;D'Ilario, Lucio;Martinelli, Andrea;Piozzi, Antonella
2010
Abstract
Novel core–shell magnetic nanocomposites for drug targeting of anticancer drugs were developed by a reverse emulsion process. Two different nanoparticle coatings (albumin and polyethylene oxide) were investigated to elucidate their possible role in controlling drug adsorption and release of methotrexate, used as model anticancer drug. The obtained results evidenced as these formulations may be potentially employed as effective carriers for drug targeting.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
