Lipolytic enzymes represent an important class of biocatalysts and are widely used in the resolution of racemic mixtures. The activity of lipase from Candida cylindracea at different temperatures has been studied by NMR determination of the enantiomeric excess in the enantioselective hydrolysis of 2-arylpropionic acid esters of pharmacological interest. At a purpose, a system based on Europium (III) chiral shift reagent has been settled and utilized.

Enzymatic catalysis by lipase from Candida cylindracea: enantiomeric activity evaluation by 1H and 13C NMR / Cernia, Enrico; Delfini, Maurizio; Magri', Andrea; Palocci, Cleofe. - In: CELLULAR AND MOLECULAR BIOLOGY. - ISSN 0145-5680. - STAMPA. - 40:2(1994), pp. 193-199.

Enzymatic catalysis by lipase from Candida cylindracea: enantiomeric activity evaluation by 1H and 13C NMR.

CERNIA, Enrico;DELFINI, Maurizio;MAGRI', Andrea;PALOCCI, Cleofe
1994

Abstract

Lipolytic enzymes represent an important class of biocatalysts and are widely used in the resolution of racemic mixtures. The activity of lipase from Candida cylindracea at different temperatures has been studied by NMR determination of the enantiomeric excess in the enantioselective hydrolysis of 2-arylpropionic acid esters of pharmacological interest. At a purpose, a system based on Europium (III) chiral shift reagent has been settled and utilized.
1994
2-arylpropionic acids; bioconversion; chiral molecules; enzymatic hydrolysis; shift reagent
01 Pubblicazione su rivista::01a Articolo in rivista
Enzymatic catalysis by lipase from Candida cylindracea: enantiomeric activity evaluation by 1H and 13C NMR / Cernia, Enrico; Delfini, Maurizio; Magri', Andrea; Palocci, Cleofe. - In: CELLULAR AND MOLECULAR BIOLOGY. - ISSN 0145-5680. - STAMPA. - 40:2(1994), pp. 193-199.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/19365
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