Background: The purpose of the present study was to assess right ventricular function in Ebstein’s patients (pts) using tissue Doppler imaging (TDI) and strain Doppler imaging (SRI) echocardiography and radionuclide angiocardiography (RNA) to better understand the relationship between functional severity and anatomic derangement. Methods: Echocardiography with TDI and strain capabilities was performed in 12 pts aged 14-66 years. 10 age- and gender-matched subjects with no signs of heart disease were selected as normal controls (CTR). Right ventricular ejection fraction (RVEF), fractional shortening (RVFS), and tricuspid flow filling parameters (E/A ratio, DT) were determined. Offline analysis of the myocardial velocity data sets was performed using dedicated software. Velocity and strain traces from right ventricular free wall (RVFW) were processed in the apical 4-chamber view. Systolic and diastolic TDI values (Sw, Ew, Aw), peak systolic strain and systolic and diastolic strain rate values were determined. Echocardiographic parameters of RV longitudinal function were compared with estimates of the RVEF obtained by radionuclide imaging. Results: Ew/Aw ratio was significantly reduced in pts compared to CTR (p<0.005). Peak systolic strain and systolic and diastolic strain rate at apical and mid level were also lower in pts than in CTR (p<0.001). RVEF, RVFS, E/A ratio, and DT were not significantly different among the two groups. No correlation was found between RVEF, RVFS, E/A ratio, DT, and anatomic derangement. A significant relationship was shown between peak systolic strain and the ratio of proximal to distal right ventricle (r=-0.71, p<0.001) and between peak systolic strain and apical displacement of septal/posterior leaflet (r=-0.56, p<0.05). A significant relationship was also obtained between systolic strain at RVFW site and radionuclide RVEF (r=0.79, p<0.001) and peak systolic strain rate at RVFW site and radionuclide RVEF (r=0.83, p<0.001). Conclusion: Ebstein’s pts may present with systo-diastolic ventricular dysfunction that can be assessed by strain Doppler echocardiography. Its role in the assessment of this disease in view of medical and surgical approaches should be evaluated in a larger series of patients.
Assessment of right ventricular function in Ebstein disease: A comparison between strain Doppler echocardiography and radionuclide angiocardiography / Vitarelli, Antonino; Conde, Y; Cimino, E; D'Orazio, Simona; Stellato, Simona; Battaglia, Daniela; Padella, V; Caranci, Fiorella; Continanza, Giovanna; CORTES MORICHETTI, M.. - In: EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY. - ISSN 1525-2167. - STAMPA. - (2007). (Intervento presentato al convegno Euroecho 11 tenutosi a Lisbon, Portugal nel 5-8 Dec. 2007).
Assessment of right ventricular function in Ebstein disease: A comparison between strain Doppler echocardiography and radionuclide angiocardiography
VITARELLI, Antonino;D'ORAZIO, SIMONA;STELLATO, SIMONA;BATTAGLIA, DANIELA;CARANCI, FIORELLA;CONTINANZA, GIOVANNA;
2007
Abstract
Background: The purpose of the present study was to assess right ventricular function in Ebstein’s patients (pts) using tissue Doppler imaging (TDI) and strain Doppler imaging (SRI) echocardiography and radionuclide angiocardiography (RNA) to better understand the relationship between functional severity and anatomic derangement. Methods: Echocardiography with TDI and strain capabilities was performed in 12 pts aged 14-66 years. 10 age- and gender-matched subjects with no signs of heart disease were selected as normal controls (CTR). Right ventricular ejection fraction (RVEF), fractional shortening (RVFS), and tricuspid flow filling parameters (E/A ratio, DT) were determined. Offline analysis of the myocardial velocity data sets was performed using dedicated software. Velocity and strain traces from right ventricular free wall (RVFW) were processed in the apical 4-chamber view. Systolic and diastolic TDI values (Sw, Ew, Aw), peak systolic strain and systolic and diastolic strain rate values were determined. Echocardiographic parameters of RV longitudinal function were compared with estimates of the RVEF obtained by radionuclide imaging. Results: Ew/Aw ratio was significantly reduced in pts compared to CTR (p<0.005). Peak systolic strain and systolic and diastolic strain rate at apical and mid level were also lower in pts than in CTR (p<0.001). RVEF, RVFS, E/A ratio, and DT were not significantly different among the two groups. No correlation was found between RVEF, RVFS, E/A ratio, DT, and anatomic derangement. A significant relationship was shown between peak systolic strain and the ratio of proximal to distal right ventricle (r=-0.71, p<0.001) and between peak systolic strain and apical displacement of septal/posterior leaflet (r=-0.56, p<0.05). A significant relationship was also obtained between systolic strain at RVFW site and radionuclide RVEF (r=0.79, p<0.001) and peak systolic strain rate at RVFW site and radionuclide RVEF (r=0.83, p<0.001). Conclusion: Ebstein’s pts may present with systo-diastolic ventricular dysfunction that can be assessed by strain Doppler echocardiography. Its role in the assessment of this disease in view of medical and surgical approaches should be evaluated in a larger series of patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
