Schistocytes are fragments of red blood cells which maybe encountered in the peripheral blood smear of patientssufering from a variety of microangiopathic diseases. In the hospitalized COVID-19 patients at diferent stages of disease severity, a schistocyte count ≥ 1% was documented in approximately 70% of patients. Evidence of myocardial injury was observed in 87.5% of all who had a count of schistocytes ≥ 1%. Schistocytes may serve as a simple and inexpensive biomarker to identify a high-risk subpopulation with a latent systemic microvascular damage irrespective of respiratory symptoms

Evidence of systemic endothelial injury and microthrombosis in hospitalized COVID-19 patients at different stages of the disease / Della Rocca, D. G.; Magnocavallo, M.; Lavalle, C.; Romero, J.; Forleo, G. B.; Tarantino, N.; Chimenti, C.; Alviz, I.; Gamero, M. T.; Garcia, M. J.; Di Biase, L.; Natale, A.. - In: JOURNAL OF THROMBOSIS AND THROMBOLYSIS. - ISSN 0929-5305. - 51:3(2021), pp. 571-576. [10.1007/s11239-020-02330-1]

Evidence of systemic endothelial injury and microthrombosis in hospitalized COVID-19 patients at different stages of the disease

Magnocavallo M.
Co-primo
;
Lavalle C.;Chimenti C.;
2021

Abstract

Schistocytes are fragments of red blood cells which maybe encountered in the peripheral blood smear of patientssufering from a variety of microangiopathic diseases. In the hospitalized COVID-19 patients at diferent stages of disease severity, a schistocyte count ≥ 1% was documented in approximately 70% of patients. Evidence of myocardial injury was observed in 87.5% of all who had a count of schistocytes ≥ 1%. Schistocytes may serve as a simple and inexpensive biomarker to identify a high-risk subpopulation with a latent systemic microvascular damage irrespective of respiratory symptoms
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/1573512
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