This nested case-cohort analysis from the multinational Prospective Urban Rural Epidemiology (PURE) study analyzed plasma levels of a component of the renin-angiotensin system (RAS), angiotensin-converting enzyme 2 (ACE2), as a predictor of cardiovascular (CV) events [CV mortality, myocardial infarction (MI), stroke, heart failure (HF)] and all-cause mortality. • From a total population of 55 246 PURE participants from 14 countries across five continents, the authors took a random sample (the subcohort). The final sample consisted of participants who were members of the subcohort (n ¼ 5084) and those who had incident events outside the subcohort (n ¼ 5669). The median follow-up was 9.4 years (IQR, 8.7–10.5).

The second life of the ambiguous angiotensin-converting enzyme 2 as a predictive biomarker for cardiometabolic diseases and death / Volpe, M.; Patrono, C.. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - 41:45(2020), pp. 4302-4303. [10.1093/eurheartj/ehaa929]

The second life of the ambiguous angiotensin-converting enzyme 2 as a predictive biomarker for cardiometabolic diseases and death

Volpe M.;Patrono C.
2020

Abstract

This nested case-cohort analysis from the multinational Prospective Urban Rural Epidemiology (PURE) study analyzed plasma levels of a component of the renin-angiotensin system (RAS), angiotensin-converting enzyme 2 (ACE2), as a predictor of cardiovascular (CV) events [CV mortality, myocardial infarction (MI), stroke, heart failure (HF)] and all-cause mortality. • From a total population of 55 246 PURE participants from 14 countries across five continents, the authors took a random sample (the subcohort). The final sample consisted of participants who were members of the subcohort (n ¼ 5084) and those who had incident events outside the subcohort (n ¼ 5669). The median follow-up was 9.4 years (IQR, 8.7–10.5).
2020
angiotensin-converting enzyme 2; biomarkers; humans; plasma; cardiovascular diseases; peptidyl-dipeptidase A
01 Pubblicazione su rivista::01b Commento, Erratum, Replica e simili
The second life of the ambiguous angiotensin-converting enzyme 2 as a predictive biomarker for cardiometabolic diseases and death / Volpe, M.; Patrono, C.. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - 41:45(2020), pp. 4302-4303. [10.1093/eurheartj/ehaa929]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1542142
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