Exercise as preventative therapy against neurodegenerative diseases in older adults

Exercise could be effective as preventative remedy against neurodegenerative diseases in older adults.[1] Exercise is neuroprotective because it has been shown to improve skills, reduce motor discrepancies, upsurge new neuron development, amend neurological damages, obstruct age-related neuronal harm, and prevent cognitive decline among older adults.[2] Physically active aged rats in comparison to inactive aged rats show enhanced three-dimensional learning, improved memory retention, and reduced age-related deteriorations in spontaneous activity.[3] Humans produce fewer insulin-like growth factor 1 (IGF-1) during normal aging process; IGF-1 plays a key role in the growth of cellular structures in a matured brain; however, exercise was found to increase the uptake of neurotropic IGF-1 from circulation directly to precise areas such as the hippocampus.