New Chemical Entities (NCEs) could be generally exposed to several stress conditions of hydrolysis, oxidation, photolysis and thermal degradation in order to better characterize the compounds and to know if the degradation processes lead to generate undesired (or toxic) products.

Investigation on the stability of new biologically active thiosemicarbazone-derived compounds by a validated HPLC-PDA method / Secci, Daniela; Locatelli, Marcello; Kabir, Abuzar; Salvatorelli, Erika; Macedonio, Giorgia; Mollica and Simone Carradori, Adriano. - In: CURRENT ANALYTICAL CHEMISTRY. - ISSN 1573-4110. - 15:3(2019), pp. 313-320. [10.2174/1573411014666180502105225]

Investigation on the stability of new biologically active thiosemicarbazone-derived compounds by a validated HPLC-PDA method

Daniela Secci
Primo
;
2019

Abstract

New Chemical Entities (NCEs) could be generally exposed to several stress conditions of hydrolysis, oxidation, photolysis and thermal degradation in order to better characterize the compounds and to know if the degradation processes lead to generate undesired (or toxic) products.
2019
forced decomposition studies; HPLC-PDA; method validation; new chemical entities; stability tests; thiosemicarbazone derivatives
01 Pubblicazione su rivista::01a Articolo in rivista
Investigation on the stability of new biologically active thiosemicarbazone-derived compounds by a validated HPLC-PDA method / Secci, Daniela; Locatelli, Marcello; Kabir, Abuzar; Salvatorelli, Erika; Macedonio, Giorgia; Mollica and Simone Carradori, Adriano. - In: CURRENT ANALYTICAL CHEMISTRY. - ISSN 1573-4110. - 15:3(2019), pp. 313-320. [10.2174/1573411014666180502105225]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1351315
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