The syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural systems that contribute to AHP, when disconnected or directly damaged: the (i) premotor loop (ii) limbic system, and (iii) ventral attentional network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.

Anosognosia for hemiplegia as a tripartite disconnection syndrome / Pacella, Valentina; Foulon, Chris; M Jenkinson, Paul; Scandola, Michele; Bertagnoli, Sara; Avesani, Renato; Fotopoulou, Aikaterini; Moro, Valentina; Thiebaut de Schotten, Michel. - In: ELIFE. - ISSN 2050-084X. - (2019). [doi.org/10.7554/eLife.46075.001]

Anosognosia for hemiplegia as a tripartite disconnection syndrome

Valentina Pacella;Sara Bertagnoli;
2019

Abstract

The syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural systems that contribute to AHP, when disconnected or directly damaged: the (i) premotor loop (ii) limbic system, and (iii) ventral attentional network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.
2019
Anosognosia for hemiplegia; disconnection; neuropsychology
01 Pubblicazione su rivista::01a Articolo in rivista
Anosognosia for hemiplegia as a tripartite disconnection syndrome / Pacella, Valentina; Foulon, Chris; M Jenkinson, Paul; Scandola, Michele; Bertagnoli, Sara; Avesani, Renato; Fotopoulou, Aikaterini; Moro, Valentina; Thiebaut de Schotten, Michel. - In: ELIFE. - ISSN 2050-084X. - (2019). [doi.org/10.7554/eLife.46075.001]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1343505
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