An examination of an adult male buried from the post-classical necropolis of La Selvicciola (Viterbo, Latium, Italy; 4th–6th centuries AD) revealed a series of skeletal lesions. The lesions, both proliferative and lytic, ranging in size from small (around 0.01 mm) to extensive (up to 16.00 mm) pits, occurred at multiple sites. A holistic approach assessed lesion type, frequency and location in a differential diagnosis, which included myeloma, metastatic carcinoma, tuberculosis, leukemia, osteomyelitis, and mycoses. It was concluded that a mycosis, specifically Cryptococcosis, was the most likely cause of these lesions. Both macroscopic analyses and X-ray scans support our diagnosis. We also provide a methodological scheme as a model for examining unknown lesion patterns.

A possible case of mycosis in a post-classical burial from La Selvicciola (Italy) / Micarelli, Ileana; Paine, Robert R.; Tafuri, Mary Anne; Manzi, Giorgio. - In: INTERNATIONAL JOURNAL OF PALEOPATHOLOGY. - ISSN 1879-9817. - ELETTRONICO. - 24:(2018), pp. 25-33. [10.1016/j.ijpp.2018.09.001]

A possible case of mycosis in a post-classical burial from La Selvicciola (Italy)

Micarelli, Ileana;Tafuri, Mary Anne
;
Manzi, Giorgio
2018

Abstract

An examination of an adult male buried from the post-classical necropolis of La Selvicciola (Viterbo, Latium, Italy; 4th–6th centuries AD) revealed a series of skeletal lesions. The lesions, both proliferative and lytic, ranging in size from small (around 0.01 mm) to extensive (up to 16.00 mm) pits, occurred at multiple sites. A holistic approach assessed lesion type, frequency and location in a differential diagnosis, which included myeloma, metastatic carcinoma, tuberculosis, leukemia, osteomyelitis, and mycoses. It was concluded that a mycosis, specifically Cryptococcosis, was the most likely cause of these lesions. Both macroscopic analyses and X-ray scans support our diagnosis. We also provide a methodological scheme as a model for examining unknown lesion patterns.
2018
mycosis; fungal infection; osteolytic lesions; post-classical Italy
01 Pubblicazione su rivista::01a Articolo in rivista
A possible case of mycosis in a post-classical burial from La Selvicciola (Italy) / Micarelli, Ileana; Paine, Robert R.; Tafuri, Mary Anne; Manzi, Giorgio. - In: INTERNATIONAL JOURNAL OF PALEOPATHOLOGY. - ISSN 1879-9817. - ELETTRONICO. - 24:(2018), pp. 25-33. [10.1016/j.ijpp.2018.09.001]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1182976
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