Immunoglobulins, C3 and C4 levels and circulating immune complexes have been measured on admission sera from 34 children admitted to a Naples hospital during the winter of 1978/79 with severe, usually fatal, acute respiratory infections and in age-matched controls from Rome. The Naples sera were characterised by low IgA, C3, and C4 levels, increased IgM and IgG concentrations, and high titres of circulating immune complexes. These immunological abnormalities could explain the high concentration of fatal cases.

Immunoglobulins, C3 and C4 levels, and circulating immune complexes have been measured on admission sera from 34 children admitted to a Naples hospital during the winter of 1978/79 with severe, usually fatal, acute respiratory infections and in age-matched controls from Rome. The Naples sera were characterised by low IgA, C3, and C4 levels, increased IgM and IgG concentrations, and high titres of circulating immune complexes. These immunological abnormalities could explain the high concentration of fatal cases.

IgA deficiency and circulating immune complexes in Neapolitan children with fatal acute respiratory infections / Aiuti, F; Valesini, G; D'Amelio, R; Luzi, G; Palmisano, L; Giunchi, G. - In: THE LANCET. - ISSN 0140-6736. - STAMPA. - 1:8162(1980), pp. 226-229. [10.1016/s0140-6736(80)90716-3]

IgA deficiency and circulating immune complexes in Neapolitan children with fatal acute respiratory infections

Aiuti, F;Valesini, G;D'Amelio, R;Giunchi, G
1980

Abstract

Immunoglobulins, C3 and C4 levels and circulating immune complexes have been measured on admission sera from 34 children admitted to a Naples hospital during the winter of 1978/79 with severe, usually fatal, acute respiratory infections and in age-matched controls from Rome. The Naples sera were characterised by low IgA, C3, and C4 levels, increased IgM and IgG concentrations, and high titres of circulating immune complexes. These immunological abnormalities could explain the high concentration of fatal cases.
1980
Immunoglobulins, C3 and C4 levels, and circulating immune complexes have been measured on admission sera from 34 children admitted to a Naples hospital during the winter of 1978/79 with severe, usually fatal, acute respiratory infections and in age-matched controls from Rome. The Naples sera were characterised by low IgA, C3, and C4 levels, increased IgM and IgG concentrations, and high titres of circulating immune complexes. These immunological abnormalities could explain the high concentration of fatal cases.
Acute Disease; Complement C3; Complement C4; Dysgammaglobulinemia; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Infant; Italy; Male; Respiratory Tract Diseases; Respiratory Tract Infections; Antigen-Antibody Complex; IgA Deficiency
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IgA deficiency and circulating immune complexes in Neapolitan children with fatal acute respiratory infections / Aiuti, F; Valesini, G; D'Amelio, R; Luzi, G; Palmisano, L; Giunchi, G. - In: THE LANCET. - ISSN 0140-6736. - STAMPA. - 1:8162(1980), pp. 226-229. [10.1016/s0140-6736(80)90716-3]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/15598
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