Background: Allergic diseases represent a frequent and increasing condition affecting children. A screening questionnaire allowing an easy identification of children with symptoms of allergic diseases may improve management and clinical outcome. The aim of this study was to develop and validate an easy-to-use screening questionnaire to detect children requiring further allergological evaluations. Methods: A 10-item questionnaire, evaluating the presence and the history of the most frequent allergic conditions affecting children, including allergic asthma, allergic rhinitis and conjunctivitis, food allergy, and atopic dermatitis, was developed and administered to 214 parents of children from 5 to 10 years of age (163 with allergic disease and 51 healthy, nonallergic children). Validation was performed by Pearson's correlation between the clinical diagnosis and the responses to the questionnaire. Internal consistency was computed by Cronbach's alpha correlation coefficient. Sensitivity and specificity of the novel questionnaire were assessed by the receiver operating characteristic (ROC) curve. Results: Validation analysis of the new children atopy (ChAt) questionnaire showed good internal consistency with a Cronbach's alpha of 0.757. Responses to the items evaluating the presence of individual allergic conditions significantly correlated with the clinical diagnosis (p<0.001). The ROC curve showed an area of 0.956 and identified a cutoff value >2 of the ChAt questionnaire total score for detection of allergy (sensitivity =0.92 and specificity =0.902). Conclusion: The novel ChAt questionnaire represents a simple tool able to detect the presence of all major allergic diseases in a pediatric population allowing an early identification of allergic multimorbidity and potentially facilitating clinical management.

Development and preliminary validation of a new screening questionnaire for identifying atopic children / Sacchetti, Marta; Ilaria, Baiardini; Loredana, Chini; Viviana, Moschese; Bruscolini, Alice; Lambiase, Alessandro. - In: PEDIATRIC HEALTH, MEDICINE AND THERAPEUTICS. - ISSN 1179-9927. - STAMPA. - 8:(2017), pp. 99-105. [10.2147/PHMT.S142271]

Development and preliminary validation of a new screening questionnaire for identifying atopic children

SACCHETTI, MARTA
Primo
;
BRUSCOLINI, ALICE
Penultimo
;
LAMBIASE, ALESSANDRO
Ultimo
2017

Abstract

Background: Allergic diseases represent a frequent and increasing condition affecting children. A screening questionnaire allowing an easy identification of children with symptoms of allergic diseases may improve management and clinical outcome. The aim of this study was to develop and validate an easy-to-use screening questionnaire to detect children requiring further allergological evaluations. Methods: A 10-item questionnaire, evaluating the presence and the history of the most frequent allergic conditions affecting children, including allergic asthma, allergic rhinitis and conjunctivitis, food allergy, and atopic dermatitis, was developed and administered to 214 parents of children from 5 to 10 years of age (163 with allergic disease and 51 healthy, nonallergic children). Validation was performed by Pearson's correlation between the clinical diagnosis and the responses to the questionnaire. Internal consistency was computed by Cronbach's alpha correlation coefficient. Sensitivity and specificity of the novel questionnaire were assessed by the receiver operating characteristic (ROC) curve. Results: Validation analysis of the new children atopy (ChAt) questionnaire showed good internal consistency with a Cronbach's alpha of 0.757. Responses to the items evaluating the presence of individual allergic conditions significantly correlated with the clinical diagnosis (p<0.001). The ROC curve showed an area of 0.956 and identified a cutoff value >2 of the ChAt questionnaire total score for detection of allergy (sensitivity =0.92 and specificity =0.902). Conclusion: The novel ChAt questionnaire represents a simple tool able to detect the presence of all major allergic diseases in a pediatric population allowing an early identification of allergic multimorbidity and potentially facilitating clinical management.
2017
allergy; children; questionnaire; screening; validation
01 Pubblicazione su rivista::01a Articolo in rivista
Development and preliminary validation of a new screening questionnaire for identifying atopic children / Sacchetti, Marta; Ilaria, Baiardini; Loredana, Chini; Viviana, Moschese; Bruscolini, Alice; Lambiase, Alessandro. - In: PEDIATRIC HEALTH, MEDICINE AND THERAPEUTICS. - ISSN 1179-9927. - STAMPA. - 8:(2017), pp. 99-105. [10.2147/PHMT.S142271]
File allegati a questo prodotto
File Dimensione Formato  
Sacchetti_Development and preliminary_2017.pdf

accesso aperto

Note: https://www.dovepress.com/development-and-preliminary-validation-of-a-new-screening-questionnair-peer-reviewed-article-PHMT
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 537.14 kB
Formato Adobe PDF
537.14 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1017919
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 4
social impact