The investigation of brand new compounds with potential anti-viral activity is currently in the limelight of worldwide research, in particular with regard to the will to eradicate the HIV virus. In this context, after the chemical synthesis approach, that has produced several drugs capable of slowing the course of the disease and improving the survival expectations, the latest research trends are involved in the search for anti-viral compounds from natural sources which could be active by themselves or may furnish their basic structures as useful building blocks to be employed in semisynthetic approaches.

Semi-synthesis of three precursors of carbocyclic nucleoside analogues / Venditti, Alessandro; Lorenzetti, Lm; Frezza, Claudio; Serafini, Mauro; Ornano, L; Bianco, Armandodoriano. - In: TRENDS IN ORGANIC CHEMISTRY. - ISSN 0972-4362. - STAMPA. - 18:(2017), pp. 101-105.

Semi-synthesis of three precursors of carbocyclic nucleoside analogues

VENDITTI, ALESSANDRO
;
FREZZA, CLAUDIO;SERAFINI, Mauro;BIANCO, Armandodoriano
2017

Abstract

The investigation of brand new compounds with potential anti-viral activity is currently in the limelight of worldwide research, in particular with regard to the will to eradicate the HIV virus. In this context, after the chemical synthesis approach, that has produced several drugs capable of slowing the course of the disease and improving the survival expectations, the latest research trends are involved in the search for anti-viral compounds from natural sources which could be active by themselves or may furnish their basic structures as useful building blocks to be employed in semisynthetic approaches.
2017
semi-synthesis; harpagide; 8-O-acetyl-harpagide; carbocyclic nucleoside analogues; anti-viral activity
01 Pubblicazione su rivista::01a Articolo in rivista
Semi-synthesis of three precursors of carbocyclic nucleoside analogues / Venditti, Alessandro; Lorenzetti, Lm; Frezza, Claudio; Serafini, Mauro; Ornano, L; Bianco, Armandodoriano. - In: TRENDS IN ORGANIC CHEMISTRY. - ISSN 0972-4362. - STAMPA. - 18:(2017), pp. 101-105.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1008974
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