Catalogo dei prodotti della ricerca

ILARI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 3.785
EU - Europa 1.631
AS - Asia 1.390
SA - Sud America 252
AF - Africa 68
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 1
Totale 7.131
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Nazione #
US - Stati Uniti d'America 3.690
IT - Italia 768
SG - Singapore 632
HK - Hong Kong 240
DE - Germania 220
BR - Brasile 202
IN - India 186
CN - Cina 183
SE - Svezia 156
FI - Finlandia 135
UA - Ucraina 80
RU - Federazione Russa 79
CA - Canada 67
GB - Regno Unito 48
TG - Togo 36
AR - Argentina 28
FR - Francia 25
BG - Bulgaria 21
JP - Giappone 21
ID - Indonesia 19
BE - Belgio 15
IE - Irlanda 15
BD - Bangladesh 14
CH - Svizzera 13
MX - Messico 13
RO - Romania 13
PK - Pakistan 12
VN - Vietnam 12
NL - Olanda 11
TR - Turchia 11
KR - Corea 9
UZ - Uzbekistan 8
ZA - Sudafrica 8
VE - Venezuela 7
AT - Austria 6
IQ - Iraq 6
IR - Iran 6
CZ - Repubblica Ceca 5
DZ - Algeria 5
EC - Ecuador 5
JM - Giamaica 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
KE - Kenya 4
LT - Lituania 4
NG - Nigeria 4
UY - Uruguay 4
BA - Bosnia-Erzegovina 3
EG - Egitto 3
EU - Europa 3
MA - Marocco 3
MY - Malesia 3
PS - Palestinian Territory 3
SA - Arabia Saudita 3
TT - Trinidad e Tobago 3
BB - Barbados 2
BH - Bahrain 2
BN - Brunei Darussalam 2
BZ - Belize 2
CO - Colombia 2
ES - Italia 2
NP - Nepal 2
OM - Oman 2
PH - Filippine 2
PL - Polonia 2
PY - Paraguay 2
AM - Armenia 1
AU - Australia 1
AZ - Azerbaigian 1
BO - Bolivia 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
GE - Georgia 1
GH - Ghana 1
GR - Grecia 1
GY - Guiana 1
IL - Israele 1
JO - Giordania 1
KG - Kirghizistan 1
KY - Cayman, isole 1
MK - Macedonia 1
MM - Myanmar 1
MW - Malawi 1
PR - Porto Rico 1
PT - Portogallo 1
RS - Serbia 1
SC - Seychelles 1
SM - San Marino 1
TN - Tunisia 1
TW - Taiwan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 7.131
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Città #
Fairfield 593
Rome 388
Singapore 326
Ashburn 316
Woodbridge 298
Hong Kong 239
Chandler 237
Seattle 217
Houston 198
Wilmington 180
Cambridge 179
Ann Arbor 163
Princeton 99
Beijing 83
Santa Clara 82
Munich 80
Plano 68
San Paolo di Civitate 68
Lawrence 64
San Diego 62
Dearborn 53
Helsinki 50
Millbury 48
Ottawa 42
Boston 38
Frankfurt am Main 36
Lomé 36
Jacksonville 33
Turku 31
Bremen 29
Boardman 26
Los Angeles 24
Andover 23
Sofia 21
Falls Church 20
Jakarta 19
Milan 19
Moscow 19
New York 19
Toronto 18
Federal 17
Fremont 16
Tokyo 16
Cosenza 15
Dublin 14
Brussels 13
Nanjing 13
Norwalk 13
Rio de Janeiro 11
San Jose 11
São Paulo 11
Bühl 10
Florence 9
London 9
Falkenstein 8
Frosinone 8
Nuremberg 8
Phoenix 8
Curitiba 7
Ferentino 7
Geneva 7
Guangzhou 7
Lahore 7
Redwood City 7
Stockholm 7
Tashkent 7
Washington 7
Hanoi 6
Ho Chi Minh City 6
Kunming 6
Naples 6
San Mateo 6
Tehran 6
Trieste 6
Urbino 6
Chicago 5
Dhaka 5
Hefei 5
Johannesburg 5
Queens 5
Shanghai 5
Baghdad 4
Bay Shore 4
Belo Horizonte 4
Council Bluffs 4
Dallas 4
Grafing 4
Kingston 4
Las Vegas 4
Marseille 4
Modena 4
Nairobi 4
New Delhi 4
Palhoça 4
Porto Alegre 4
Pune 4
Southend 4
Ankara 3
Aracaju 3
Aradeo 3
Totale 4.968
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Nome #
Leishmania infantum trypanothione reductase is a promiscuous enzyme carrying an nadph:o2 oxidoreductase activity shared by glutathione reductase 167
Identification of the pyridoxal 5′‐phosphate allosteric site in human pyridox(am)ine 5′‐phosphate oxidase 160
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 160
Engineered ferritin for lanthanide binding 147
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 141
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 136
Identification and characterization of the pyridoxal 5'-phosphate allosteric site in Escherichia coli pyridoxine 5'-phosphate oxidase 127
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 116
Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage 113
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 112
Role of a conserved active site cation-pi interaction in Escherichia coli serine hydroxymethyltransferase. 111
PIRROLIL-IDROSSAMMATI PER USO NELLA PREVENZIONE E/O NEL TRATTAMENTO DI INFEZIONI BATTERICHE 107
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme 107
Crystal structure and ligand binding properties of the truncated hemoglobin from Geobacillus stearothermophilus 106
Structural studies on flavohemoglobins. 104
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 104
Calcium- and pH-linked oligomerization of sorcin causing translocation from cytosol to membranes 104
A novel thermostable hemoglobin from the actinobacterium Thermobifida fusca. 99
Not only P-glycoprotein: amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins 99
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation 98
Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus- structural basis of substrate recognition. 95
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition. 95
Effect of the vinyl-globin interactions on the temperature-dependent broadening of the Soret spectra: A study with horse myoglobin and Scapharca dimeric hemoglobin reconstituted with unnatural 2,4-heme derivatives 95
Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review 95
Structural basis of Sorcin-mediated calcium-dependent signal transduction 95
The X-ray structure of ferric Escherichia coli flavohemoglobin reveals an unexpected geometry of the distal heme pocket 94
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures 93
Structural basis of enzymatic (S)-norcoclaurine biosynthesis 92
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 92
The mutations Lys 114 ->Gln and Asp 126 -> Asn disrupt an intersubunit salt bridge and convert Listeria innocua Dps into its natural mutant Listeria monocytogenes Dps. Effects on protein stability at low pH. 90
Binding of doxorubicin to sorcin impairs cell death and increases drug resistance in cancer cells 90
The crystal structure of Giardia duodenalis 14-3-3 in the apo form: When protein post-translational modifications make the difference 90
Taxanes in cancer treatment: activity, chemoresistance and its overcoming 90
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 88
Crystallization and preliminary X-ray crystallographic analysis of the unusual ferritin from Listeria innocua 87
The crystal structure of the sorcin calcium binding domain provides a model of Ca2+ dependent processes in the full length protein. 86
Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase center that may explain the Mn-dependent protection against oxidative stress 86
Iron oxidation and hydrolysis reactions of a novel ferritin from Listeria innocua 85
Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter 84
Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. 84
The truncated oxygen-avid hemoglobin from Bacillus subtilis: X-ray structure and ligand binding properties 83
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure? 83
Unusual heme iron-lipid acyl chain coordination in Escherichia coli flavohemoglobin 82
Escherichia coli flavohemoglobin is an efficient alkylhydroperoxide reductase 81
Metals and metal derivatives in medicine. 81
The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of Leishmania detoxification pathway. 80
Metal-based compounds as prospective antileishmanial agents: Inhibition of Trypanothione reductase by selected gold complexes 80
Sorcin, a calcium binding protein involved in the multidrug resistance mechanisms in cancer cells 80
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 79
Iron and proteins for iron storage and detoxification 78
Sorcin links calcium signaling to vesicle trafficking, regulates polo-like kinase 1 and is necessary for mitosis 77
Rigidity of the heme pocket in the cooperative Scapharca hemoglobin homodimer and relation to the direct communication between hemes. 76
UNUSUAL AFFINITY OF CYANIDE FOR FERROUS AND FERRIC SCAPHARCA INAEQUIVALVIS HOMODIMERIC HEMOGLOBIN. EQUILIBRIA AND KINETICS OF THE REACTION 75
Spiro-containing derivatives show antiparasitic activity against trypanosoma brucei through inhibition of the trypanothione reductase enzyme 74
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity 74
Crystallization and preliminary X-ray crystallographic analysis of the laminarinase endo-beta-1,3-glucanase from Pyrococcus furiosus. 72
The Salmonella enterica ZinT structure, zinc affinity and interaction with the high-affinity uptake protein ZnuA provide insight into the management of periplasmic zinc 72
Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography 71
Cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from Thalictrum flavum 68
Roles of sorcin in drug resistance in cancer: one protein, many mechanisms, for a novel potential anticancer drug target 68
null 64
From Information to Function 63
The dodecameric ferritin fron Listeria innocua contains a novel intersubunit iron-binding site 62
Inhibition of Leishmania infantum trypanothione reductase by NADPH, its natural substrate 62
Structure-function relationships in sorcin, a member of the penta EF-hand family. Interaction of sorcin fragments with the ryanodine receptor and an E.coli model system 62
Fragment merging, growing, and linking identify new trypanothione reductase inhibitors for Leishmaniasis 60
Molecular basis of antimony treatment in leishmaniasis 53
Inhibitory effect of silver nanoparticles on trypanothione reductase activity and leishmania infantum proliferation 53
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Huntingtin ubiquitination mechanisms and novel possible therapies to decrease the toxic effects of mutated huntingtin 52
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 51
Plasticity of secondary structure in the N-terminal region of beta-dystroglycan. 50
Two different crystal forms of sorcin, a penta-EF-handed Ca2+-binding protein 49
Silver Ion Incorporation and Nanoparticle Formation inside the Cavity of Pyrococcus furiosus Ferritin: Structural and Size-Distribution Analyses 48
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The unusual intersubunit ferroxidase center of Listeria innocua Dps is required for hydrogen peroxide detoxification, but not for iron uptake. A study with site-specific mutants. 46
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A novel antimicrobial approach based on the inhibition of zinc uptake in Salmonella enterica 45
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Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 42
Trypanothione reductase from leishmania infantum: cloning, expression, purification, crystallization and preliminary x-ray data analysis 42
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis 40
Disclosing the Molecular Mechanism of Iron Incorporation in Listeria innocua Dps by EPR Spectroscopy 40
The unusual dodecameric ferritin from Listeria innocua dissociates below pH 2.0 38
Target highlights in CASP14: Analysis of models by structure providers 38
New Heterocyclic Compounds Targeting Trypanothyione Metabolism in Leishmania Parasites 36
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Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 35
Iron incorporation into Escherichia coli Dps gives rise to a ferritin-like microcrystalline core 35
Iron and hydrogen peroxide detoxification properties of DNA-binding protein from starved cells. A ferritin-like DNA-binding protein of Escherichia coli 35
ZnuA, the soluble component of the bacterial Zn(II) ABC transporter, a possible target for novel antibiotics 33
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 32
null 27
Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions 27
Study of manganese binding to the ferroxidase centre of human H-type ferritin 27
Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases 25
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Totale 7.400
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Categoria #
all - tutte 21.988
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 224
selected - selezionate 0
volume - volumi 0
Totale 22.212
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021587 60 44 16 54 7 61 33 40 52 155 42 23
2021/2022957 35 63 89 26 114 30 22 109 90 60 166 153
2022/20231.042 197 214 41 132 110 73 37 53 100 23 35 27
2023/2024608 37 63 31 47 48 114 16 70 16 66 46 54
2024/20251.874 49 41 64 122 96 89 117 106 362 172 134 522
2025/2026188 188 0 0 0 0 0 0 0 0 0 0 0
Totale 7.400