Sfoglia per Autore FIORENTINO, FRANCESCO
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence
2023 Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hüben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong
Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity
2023 Fioravanti, Rossella; Proia, Eleonora; Tyurenkov, Ivan N; Kurkin, Denis V; Bakulin, Dmitry A; Kovalev, Nikolay S; Sheikin, Dmitry S; Kirillov, Ivan A; Nawrozkij, Maxim B; Vernigora, Andrey A; Brunilina, Leila L; Fiorentino, Francesco; Mladenović, Milan; Rotili, Dante; Ragno, Rino
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8
2023 Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, FRANCESCA ROMANA; Iuzzolino, Angela; D'Acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante
Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation
2023 Fiorentino, Francesco; Rotili, Dante; Mai, Antonello
Rationalizing the Optimization of Detergents for Membrane Protein Purification
2023 Urner, Leonhard H; Junge, Florian; Fiorentino, Francesco; El-Baba, Tarick J; Shutin, Denis; Nölte, Gideon; Haag, Rainer; Robinson, Carol V
METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey
2023 Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello
Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII
2023 Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello
Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection
2023 Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante
Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1
2022 Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
2022 Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A.
Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription
2022 Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio
Mass Spectrometry Analysis of Dynamics and Interactions of the LPS Translocon LptDE
2022 Fiorentino, Francesco; Bolla, Jani R
Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies
2022 Taurone, Samanta; DE PONTE, Chiara; Rotili, Dante; DE SANTIS, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra
Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5
2022 Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D.
Sirtuin modulators: past, present, and future perspectives
2022 Fiorentino, Francesco; Mautone, Nicola; Menna, Martina; D'Acunzo, Francesca; Mai, Antonello; Rotili, Dante
The two-faced role of sirt6 in cancer
2021 Fiorentino, F.; Carafa, V.; Favale, G.; Altucci, L.; Mai, A.; Rotili, D.
Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide
2021 Fiorentino, F.; Sauer, J. B.; Qiu, X.; Corey, R. A.; Cassidy, C. K.; Mynors-Wallis, B.; Mehmood, S.; Bolla, J. R.; Stansfeld, P. J.; Robinson, C. V.
Mass spectrometry informs the structure and dynamics of membrane proteins involved in lipid and drug transport
2021 Bolla, J. R.; Fiorentino, F.; Robinson, C. V.
NaViA: A Program for the Visual Analysis of Complex Mass Spectra
2021 Quetschlich, Daniel; Esser, Tim K; Newport, Thomas D; Fiorentino, Francesco; Shutin, Denis; Chen, Siyun; Davis, Rachel; Lovera, Silvia; Liko, Idlir; Stansfeld, Phillip J; Robinson, Carol V
Emerging Therapeutic Potential of SIRT6 Modulators
2021 Fiorentino, F.; Mai, A.; Rotili, D.
Anionic Dendritic Polyglycerol for Protein Purification and Delipidation
2021 Urner, L. H.; Mohammadifar, E.; Ludwig, K.; Shutin, D.; Fiorentino, F.; Liko, I.; Almeida, F. G.; Kutifa, D.; Haag, R.; Robinson, C. V.
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
2021 Fiorentino, Francesco; DE ANGELIS, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D’Acunzo, Francesca; Palamara, ANNA TERESA; Nencioni, Lucia; Rotili, Dante; Mai, Antonello
Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions
2021 Fiorentino, F.; Rotili, D.; Mai, A.; Bolla, J. R.; Robinson, C. V.
Lysine Acetyltransferase Inhibitors From Natural Sources
2020 Fiorentino, F.; Mai, A.; Rotili, D.
Assembly and regulation of the chlorhexidine-specific efflux pump AceI
2020 Bolla, J. R.; Howes, A. C.; Fiorentino, F.; Robinson, C. V.
Investigating the Conformational Dynamics of the Outer Membrane LPS Translocon LptDE
2020 Fiorentino, Francesco; Yu Qiu, Xing; Sauer, Joshua B.; Reddy Bolla, Jani; Mehmood, Shahid; Stansfeld, Phillip J.; Robinson, Carol V.
Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex
2020 Mcdowell, M. A.; Heimes, M.; Fiorentino, F.; Mehmood, S.; Farkas, A.; Coy-Vergara, J.; Wu, D.; Bolla, J. R.; Schmid, V.; Heinze, R.; Wild, K.; Flemming, D.; Pfeffer, S.; Schwappach, B.; Robinson, C. V.; Sinning, I.
HAT inhibitors in cancer therapy
2020 Fiorentino, Francesco; Mai, Antonello; Rotili, Dante
The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters
2019 Fiorentino, F.; Bolla, J. R.; Mehmood, S.; Robinson, C. V.
The Influence of Substrates and Nucleotides on Complex Formation in ABC Transporters – Insights from Mass Spectrometry
2018 Fiorentino, Francesco; Reddy Bolla, Jani; Mehmood, Shahid; Robinson, Carol V.
Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications
2018 Fiorentino, Francesco; Mai, Antonello; Rotili, Dante
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence | 2023 | Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hüben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong | |
| Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity | 2023 | Fioravanti, Rossella; Proia, Eleonora; Tyurenkov, Ivan N; Kurkin, Denis V; Bakulin, Dmitry A; Kovalev, Nikolay S; Sheikin, Dmitry S; Kirillov, Ivan A; Nawrozkij, Maxim B; Vernigora, Andrey A; Brunilina, Leila L; Fiorentino, Francesco; Mladenović, Milan; Rotili, Dante; Ragno, Rino | |
| First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8 | 2023 | Fiorentino, Francesco; Sementilli, Sara; Menna, Martina; Turrisi, Federica; Tomassi, Stefano; Pellegrini, FRANCESCA ROMANA; Iuzzolino, Angela; D'Acunzo, Francesca; Feoli, Alessandra; Wapenaar, Hannah; Taraglio, Sophie; Fraschetti, Caterina; Del Bufalo, Donatella; Sbardella, Gianluca; Dekker, Frank J.; Paiardini, Alessandro; Trisciuoglio, Daniela; Mai, Antonello; Rotili, Dante | |
| Native mass spectrometry-directed drug discovery: Recent advances in investigating protein function and modulation | 2023 | Fiorentino, Francesco; Rotili, Dante; Mai, Antonello | |
| Rationalizing the Optimization of Detergents for Membrane Protein Purification | 2023 | Urner, Leonhard H; Junge, Florian; Fiorentino, Francesco; El-Baba, Tarick J; Shutin, Denis; Nölte, Gideon; Haag, Rainer; Robinson, Carol V | |
| METTL3 from Target Validation to the First Small-Molecule Inhibitors: A Medicinal Chemistry Journey | 2023 | Fiorentino, Francesco; Menna, Martina; Rotili, Dante; Valente, Sergio; Mai, Antonello | |
| Antihistamines, phenothiazine-based antipsychotics, and tricyclic antidepressants potently activate pharmacologically relevant human carbonic anhydrase isoforms II and VII | 2023 | Fiorentino, Francesco; Nocentini, Alessio; Rotili, Dante; Supuran, Claudiu T; Mai, Antonello | |
| Emerging Roles of SIRT5 in Metabolism, Cancer, and SARS-CoV-2 Infection | 2023 | Fabbrizi, Emanuele; Fiorentino, Francesco; Carafa, Vincenzo; Altucci, Lucia; Mai, Antonello; Rotili, Dante | |
| Modulation of virulence-associated traits in Aspergillus fumigatus by BET Inhibitor JQ1 | 2022 | Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna; Orekhova, Anastasia; De Angelis, Marta; Cacciotti, Andrea; Reverberi, Massimo; Rotili, Dante; Giorgi, Alessandra; Protto, Virginia; Bonincontro, Graziana; Fiorentino, Francesco; Zgoda, Victor; Mai, Antonello; Palamara, Anna Teresa; Simonetti, Giovanna | |
| Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models | 2022 | Menna, M.; Fiorentino, F.; Marrocco, B.; Lucidi, A.; Tomassi, S.; Cilli, D.; Romanenghi, M.; Cassandri, M.; Pomella, S.; Pezzella, M.; Del Bufalo, D.; Zeya Ansari, M. S.; Tomasevic, N.; Mladenovic, M.; Viviano, M.; Sbardella, G.; Rota, R.; Trisciuoglio, D.; Minucci, S.; Mattevi, A.; Rotili, D.; Mai, A. | |
| Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription | 2022 | Minisini, Martina; Di Giorgio, Eros; Kerschbamer, Emanuela; Dalla, Emiliano; Faggiani, Massimo; Franforte, Elisa; Meyer-Almes, Franz-Josef; Ragno, Rino; Antonini, Lorenzo; Mai, Antonello; Fiorentino, Francesco; Rotili, Dante; Chinellato, Monica; Perin, Stefano; Cendron, Laura; Weichenberger, Christian X; Angelini, Alessandro; Brancolini, Claudio | |
| Mass Spectrometry Analysis of Dynamics and Interactions of the LPS Translocon LptDE | 2022 | Fiorentino, Francesco; Bolla, Jani R | |
| Biochemical functions and clinical characterizations of the sirtuins in diabetes-induced retinal pathologies | 2022 | Taurone, Samanta; DE PONTE, Chiara; Rotili, Dante; DE SANTIS, Elena; Mai, Antonello; Fiorentino, Francesco; Scarpa, Susanna; Artico, Marco; Micera, Alessandra | |
| Therapeutic Potential and Activity Modulation of the Protein Lysine Deacylase Sirtuin 5 | 2022 | Fiorentino, F.; Castiello, C.; Mai, A.; Rotili, D. | |
| Sirtuin modulators: past, present, and future perspectives | 2022 | Fiorentino, Francesco; Mautone, Nicola; Menna, Martina; D'Acunzo, Francesca; Mai, Antonello; Rotili, Dante | |
| The two-faced role of sirt6 in cancer | 2021 | Fiorentino, F.; Carafa, V.; Favale, G.; Altucci, L.; Mai, A.; Rotili, D. | |
| Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide | 2021 | Fiorentino, F.; Sauer, J. B.; Qiu, X.; Corey, R. A.; Cassidy, C. K.; Mynors-Wallis, B.; Mehmood, S.; Bolla, J. R.; Stansfeld, P. J.; Robinson, C. V. | |
| Mass spectrometry informs the structure and dynamics of membrane proteins involved in lipid and drug transport | 2021 | Bolla, J. R.; Fiorentino, F.; Robinson, C. V. | |
| NaViA: A Program for the Visual Analysis of Complex Mass Spectra | 2021 | Quetschlich, Daniel; Esser, Tim K; Newport, Thomas D; Fiorentino, Francesco; Shutin, Denis; Chen, Siyun; Davis, Rachel; Lovera, Silvia; Liko, Idlir; Stansfeld, Phillip J; Robinson, Carol V | |
| Emerging Therapeutic Potential of SIRT6 Modulators | 2021 | Fiorentino, F.; Mai, A.; Rotili, D. | |
| Anionic Dendritic Polyglycerol for Protein Purification and Delipidation | 2021 | Urner, L. H.; Mohammadifar, E.; Ludwig, K.; Shutin, D.; Fiorentino, F.; Liko, I.; Almeida, F. G.; Kutifa, D.; Haag, R.; Robinson, C. V. | |
| Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives | 2021 | Fiorentino, Francesco; DE ANGELIS, Marta; Menna, Martina; Rovere, Annarita; Maria Caccuri, Anna; D’Acunzo, Francesca; Palamara, ANNA TERESA; Nencioni, Lucia; Rotili, Dante; Mai, Antonello | |
| Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein-protein interactions | 2021 | Fiorentino, F.; Rotili, D.; Mai, A.; Bolla, J. R.; Robinson, C. V. | |
| Lysine Acetyltransferase Inhibitors From Natural Sources | 2020 | Fiorentino, F.; Mai, A.; Rotili, D. | |
| Assembly and regulation of the chlorhexidine-specific efflux pump AceI | 2020 | Bolla, J. R.; Howes, A. C.; Fiorentino, F.; Robinson, C. V. | |
| Investigating the Conformational Dynamics of the Outer Membrane LPS Translocon LptDE | 2020 | Fiorentino, Francesco; Yu Qiu, Xing; Sauer, Joshua B.; Reddy Bolla, Jani; Mehmood, Shahid; Stansfeld, Phillip J.; Robinson, Carol V. | |
| Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex | 2020 | Mcdowell, M. A.; Heimes, M.; Fiorentino, F.; Mehmood, S.; Farkas, A.; Coy-Vergara, J.; Wu, D.; Bolla, J. R.; Schmid, V.; Heinze, R.; Wild, K.; Flemming, D.; Pfeffer, S.; Schwappach, B.; Robinson, C. V.; Sinning, I. | |
| HAT inhibitors in cancer therapy | 2020 | Fiorentino, Francesco; Mai, Antonello; Rotili, Dante | |
| The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters | 2019 | Fiorentino, F.; Bolla, J. R.; Mehmood, S.; Robinson, C. V. | |
| The Influence of Substrates and Nucleotides on Complex Formation in ABC Transporters – Insights from Mass Spectrometry | 2018 | Fiorentino, Francesco; Reddy Bolla, Jani; Mehmood, Shahid; Robinson, Carol V. | |
| Lysine acetyltransferase inhibitors: structure-activity relationships and potential therapeutic implications | 2018 | Fiorentino, Francesco; Mai, Antonello; Rotili, Dante |
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