Sfoglia per Autore
Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma
2016 Granato, Marisa; Rizzello, Celeste; Romeo, Maria Anele; Yadav, Shivangi; Santarelli, Roberta; D'Orazi, Gabriella; Faggioni, Alberto; Cirone, Mara
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy
2017 Granato, Marisa; Romeo, Maria Anele; Tiano, Mariangela Sara; Santarelli, Roberta; Gonnella, Roberta; Gilardini Montani, Maria Saveria; Faggioni, Alberto; Cirone, Mara
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation
2017 Granato, Marisa; Gilardini Montani, Maria Saveria; Romeo, Maria Anele; Santarelli, Roberta; Gonnella, Roberta; D'Orazi, Gabriella; Faggioni, Alberto; Cirone, Mara
Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease?
2019 Romeo, Ma; Faggioni, A; Cirone, M
HHV-6B reduces autophagy and induces ER stress in primary monocytes impairing their survival and differentiation into dendritic cells
2019 Romeo, M. A.; Gilardini Montani, M. S.; Falcinelli, L.; Gaeta, A.; Nazzari, C.; Faggioni, A.; Cirone, M.
Kaposi Sarcoma Herpes Virus (KSHV) infection inhibits macrophage formation and survival by counteracting Macrophage Colony-Stimulating Factor (M-CSF)-induced increase of Reactive Oxygen Species (ROS), c-Jun N-terminal kinase (JNK) phosphorylation and autophagy
2019 Gilardini Montani, M. S.; Falcinelli, L.; Santarelli, R.; Romeo, M. A.; Granato, M.; Faggioni, A.; Cirone, M.
Stat3 phosphorylation affects p53/p21 axis and KSHV lytic cycle activation
2019 Santarelli, R; Carillo, V; Romeo, Ma; Gaeta, A; Nazzari, C; Gonnella, R; Granato, M; D'Orazi, G; Faggioni, A; Cirone, M
Impact of HHV-6A and HHV-6B lytic infection on autophagy and endoplasmic reticulum stress
2019 Romeo, Maria Anele; Masuelli, Laura; Gaeta, Aurelia; Nazzari, Cristina; Granato, Marisa; GILARDINI MONTANI, MARIA SAVERIA; Faggioni, Alberto; Cirone, Mara
Quercetin interrupts the positive feedback loop between STAT3 and IL-6, promotes autophagy, and reduces ROS, preventing EBV-driven B cell immortalization
2019 Granato, M.; Gilardini Montani, M. S.; Zompetta, C.; Santarelli, R.; Gonnella, R.; Romeo, M. A.; D'Orazi, G.; Faggioni, A.; Cirone, M.
Mutant p53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and p62 that induces chemio-resistance to Apigenin in pancreatic cancer cells
2019 Gilardini Montani, Ms; Cecere, N; Granato, M; Romeo, Ma; Falcinelli, L; Ciciarelli, U; D'Orazi, G; Faggioni, A; Cirone, M
STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway
2020 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Santarelli, R.; D'Orazi, G.; Cirone, M.
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease
2020 Romeo, Maria Anele; Gilardini Montani, M. S.; Gaeta, A.; D'Orazi, G.; Faggioni, A.; Cirone, M.
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression
2020 Gilardini Montani, M. S.; Falcinelli, L.; Santarelli, R.; Granato, M.; Romeo, M. A.; Cecere, N.; Gonnella, R.; D'Orazi, G.; Faggioni, A.; Cirone, M.
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR
2020 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Garufi, A.; D'Orazi, G.; Cirone, M.
Viral Infection and Autophagy Dysregulation. The Case of HHV-6, EBV and KSHV
2020 Romeo, M. A.; Santarelli, R.; Gilardini Montani, M. S.; Gonnella, R.; Benedetti, R.; Faggioni, A.; Cirone, M.
KSHV dysregulates bulk macroautophagy, mitophagy and UPR to promote endothelial to mesenchymal transition and CCL2 release, key events in viral-driven sarcomagenesis
2020 Santarelli, Roberta; Arteni, Ana Maria Brindusa; Gilardini Montani, Maria Saveria; Romeo, Maria Anele; Gaeta, Aurelia; Gonnella, Roberta; Faggioni, Alberto; Cirone, Mara
Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross-talk with p53 to activate p21
2021 Santarelli, R.; Pompili, C.; Gilardini Montani, M. S.; Romeo, M. A.; Gonnella, R.; D'Orazi, G.; Cirone, M.
p53-R273H Sustains ROS, Pro-Inflammatory Cytokine Release and mTOR Activation While Reducing Autophagy, Mitophagy and UCP2 Expression, Effects Prevented by wtp53
2021 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; D'Orazi, G.; Cirone, M.
Ire1 alpha/xbp1 axis sustains primary effusion lymphoma cell survival by promoting cytokine release and stat3 activation
2021 Gonnella, R.; Gilardini Montani, M. S.; Guttieri, L.; Romeo, M. A.; Santarelli, R.; Cirone, M.
Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53
2021 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Arena, A.; Maretto, M.; Bassetti, E.; Caiazzo, R.; D'Orazi, G.; Cirone, M.
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