Sfoglia per Autore
Generation of interleukin-6 receptor antagonists by molecular-modeling guided mutagenesis of residues important for gp130 activation.
1994 Savino, R; Lahm, H; SALVATI A., L; Ciapponi, Laura; Sporeno, E; Altamura, S; Paonessa, G; Toniatti, C; Ciliberto, G.
Rational design of a receptor super-antagonist of human interleukin-6.
1994 Savino, R; Ciapponi, Laura; Lahm, H; Demartis, A; Cabibbo, A; Toniatti, C; Delmastro, P; Altamura, S; Ciliberto, G.
GENERATION OF IL-6 ANTAGONISTS BY SUBSTITUTING RESIDUES IN HELIX-A
1994 R., Savino; A., Lahm; Lahm, ; A. L., Salvati; Ciapponi, Laura; E., Sporeno; S., Altamura; G., Paonessa; C., Toniatti; G., Ciliberto
Definition of a complex binding site for gp130 in human interleukin-6
1995 Ciapponi, Laura; Graziani, R; Paonessa, G; Lahm, A; Ciliberto, G; Savino, R.
Two distinct and independent sites on IL-6 trigger gp130 dimer formation and signalling.
1995 Paonessa, G; Graziani, R; DE SERIO, A; Savino, R; Ciapponi, Laura; Lahm, A; Salvati, Al; Toniatti, C; Ciliberto, G.
In vitro activity of two IL-6 receptor super-antagonists on Multiple Myeloma cells.
1995 Petrucci, Mt; Ricciardi, Maria Rosaria; Ciapponi, Laura; Sporeno, E; Ciliberto, G; Mandelli, Franco; Tafuri, Agostino
The molecular design of human IL-6 receptor antagonists.
1995 Lahm, A; Savino, R; SALVATI A., L; Cabibbo, A; Ciapponi, Laura; Demartis, A; Toniatti, C; Paonessa, G; Altamura, S; Ciliberto, G. A.
Human IL-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells.
1996 Sporeno, E; Savino, R; Ciapponi, Laura; Paonessa, G; Cabibbo, A; Lahm, A; Pulkki, K; SUN R., X; Toniatti, C; Klein, B; Ciliberto, G.
Cytokine gene expression in intestine of rat during the postnatal developmental period: increased IL-1 expression at weaning.
1996 Mengheri, E; Ciapponi, Laura; Vignolini, F; NOBILI F., LIFE SCIENCES
The receptor super-antagonist Sant7
1997 R., Savino; A., Demartis; Ciapponi, Laura; E., Sporeno; C., Toniatti; F., Bernassola; G., Melino; B., Klein; G., Ciliberto
IL-6 Mutants inhibit proliferation and induce apoptosis in multiple myeloma cells of patients characterized by high levels of soluble IL-6 receptor.
1997 Petrucci, Mt; Ricciardi, Maria Rosaria; Ariola, C; Gregorj, C; Ciapponi, Laura; Savino, R; Ciliberto, G; Tafuri, Agostino
Adenovirus-mediated gene transfer of an IL-6 antagonist
1997 Saggio, Isabella; Ciapponi, Laura; R., Savino; G., Ciliberto; M., Perricaudet
Induction of interleukin-6 (IL-6) autoantibodies through vaccination with an engineered IL-6 receptor antagonist.
1997 Ciapponi, Laura; Maione, D; Scoumanne, D; Costa, P; Hansen, Mb; Svenson, M; Bendtzen, K; Alonzi, T; Paonessa, G; Cortese, R; Ciliberto, G; Savino, R.
Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites.
2001 Ciapponi, Laura; Jackson, D; Mlozik, M; Bohmann, D.
Effects of IL-6 variants in multiple myeloma: Growth inhibition and induction of apoptosis in primary cells
2002 Maria Teresa, Petrucci; Ricciardi, Maria Rosaria; Chiara, Gregorj; Ciapponi, Laura; Rocco, Savino; Gennaro, Ciliberto; Tafuri, Agostino
An essential function of AP-1 heterodimers in Drosophila.
2002 Ciapponi, Laura; D., Bohmann
High circulating levels of biologically inactive IL-6/SIL-6 receptor complexes in systemic juvenile idiopathic arthritis: evidence for serum factors interfering with the binding to gp130
2003 Pignatti, P; Ciapponi, Laura; Galle, P; HANSEN M., B; Massa, M; Meazza, C; Paonessa, G; Novick, D; Ciliberto, G; Martini, A; DE BENEDETTI, F.
The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage.
2004 Ciapponi, Laura; Cenci, Giovanni; Ducau, J.; Flores, C.; JOHNSON SCHLITZ, D.; Gorski, M. M.; Engels, W. R.; Gatti, Maurizio
The mechanism of telomere protection: a comparison between Drosophila and humans
2005 Cenci, Giovanni; Ciapponi, Laura; Gatti, Maurizio
The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability
2006 Ciapponi, Laura; Cenci, Giovanni; Gatti, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Generation of interleukin-6 receptor antagonists by molecular-modeling guided mutagenesis of residues important for gp130 activation. | 1994 | Savino, R; Lahm, H; SALVATI A., L; Ciapponi, Laura; Sporeno, E; Altamura, S; Paonessa, G; Toniatti, C; Ciliberto, G. | |
| Rational design of a receptor super-antagonist of human interleukin-6. | 1994 | Savino, R; Ciapponi, Laura; Lahm, H; Demartis, A; Cabibbo, A; Toniatti, C; Delmastro, P; Altamura, S; Ciliberto, G. | |
| GENERATION OF IL-6 ANTAGONISTS BY SUBSTITUTING RESIDUES IN HELIX-A | 1994 | R., Savino; A., Lahm; Lahm, ; A. L., Salvati; Ciapponi, Laura; E., Sporeno; S., Altamura; G., Paonessa; C., Toniatti; G., Ciliberto | |
| Definition of a complex binding site for gp130 in human interleukin-6 | 1995 | Ciapponi, Laura; Graziani, R; Paonessa, G; Lahm, A; Ciliberto, G; Savino, R. | |
| Two distinct and independent sites on IL-6 trigger gp130 dimer formation and signalling. | 1995 | Paonessa, G; Graziani, R; DE SERIO, A; Savino, R; Ciapponi, Laura; Lahm, A; Salvati, Al; Toniatti, C; Ciliberto, G. | |
| In vitro activity of two IL-6 receptor super-antagonists on Multiple Myeloma cells. | 1995 | Petrucci, Mt; Ricciardi, Maria Rosaria; Ciapponi, Laura; Sporeno, E; Ciliberto, G; Mandelli, Franco; Tafuri, Agostino | |
| The molecular design of human IL-6 receptor antagonists. | 1995 | Lahm, A; Savino, R; SALVATI A., L; Cabibbo, A; Ciapponi, Laura; Demartis, A; Toniatti, C; Paonessa, G; Altamura, S; Ciliberto, G. A. | |
| Human IL-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells. | 1996 | Sporeno, E; Savino, R; Ciapponi, Laura; Paonessa, G; Cabibbo, A; Lahm, A; Pulkki, K; SUN R., X; Toniatti, C; Klein, B; Ciliberto, G. | |
| Cytokine gene expression in intestine of rat during the postnatal developmental period: increased IL-1 expression at weaning. | 1996 | Mengheri, E; Ciapponi, Laura; Vignolini, F; NOBILI F., LIFE SCIENCES | |
| The receptor super-antagonist Sant7 | 1997 | R., Savino; A., Demartis; Ciapponi, Laura; E., Sporeno; C., Toniatti; F., Bernassola; G., Melino; B., Klein; G., Ciliberto | |
| IL-6 Mutants inhibit proliferation and induce apoptosis in multiple myeloma cells of patients characterized by high levels of soluble IL-6 receptor. | 1997 | Petrucci, Mt; Ricciardi, Maria Rosaria; Ariola, C; Gregorj, C; Ciapponi, Laura; Savino, R; Ciliberto, G; Tafuri, Agostino | |
| Adenovirus-mediated gene transfer of an IL-6 antagonist | 1997 | Saggio, Isabella; Ciapponi, Laura; R., Savino; G., Ciliberto; M., Perricaudet | |
| Induction of interleukin-6 (IL-6) autoantibodies through vaccination with an engineered IL-6 receptor antagonist. | 1997 | Ciapponi, Laura; Maione, D; Scoumanne, D; Costa, P; Hansen, Mb; Svenson, M; Bendtzen, K; Alonzi, T; Paonessa, G; Cortese, R; Ciliberto, G; Savino, R. | |
| Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites. | 2001 | Ciapponi, Laura; Jackson, D; Mlozik, M; Bohmann, D. | |
| Effects of IL-6 variants in multiple myeloma: Growth inhibition and induction of apoptosis in primary cells | 2002 | Maria Teresa, Petrucci; Ricciardi, Maria Rosaria; Chiara, Gregorj; Ciapponi, Laura; Rocco, Savino; Gennaro, Ciliberto; Tafuri, Agostino | |
| An essential function of AP-1 heterodimers in Drosophila. | 2002 | Ciapponi, Laura; D., Bohmann | |
| High circulating levels of biologically inactive IL-6/SIL-6 receptor complexes in systemic juvenile idiopathic arthritis: evidence for serum factors interfering with the binding to gp130 | 2003 | Pignatti, P; Ciapponi, Laura; Galle, P; HANSEN M., B; Massa, M; Meazza, C; Paonessa, G; Novick, D; Ciliberto, G; Martini, A; DE BENEDETTI, F. | |
| The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage. | 2004 | Ciapponi, Laura; Cenci, Giovanni; Ducau, J.; Flores, C.; JOHNSON SCHLITZ, D.; Gorski, M. M.; Engels, W. R.; Gatti, Maurizio | |
| The mechanism of telomere protection: a comparison between Drosophila and humans | 2005 | Cenci, Giovanni; Ciapponi, Laura; Gatti, Maurizio | |
| The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability | 2006 | Ciapponi, Laura; Cenci, Giovanni; Gatti, Maurizio |
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