Amelioration for Allergic Rhinitis and Asthma: The Treated Yeast Milmed and Physical Exercise Immunology and Allergy

In the developed, industrial world, about 20% of people are affected by allergic rhinitis, about 6% of people have at least one food allergy, and about 20% have a topic dermatitis at some point in time. The global prevalence of allergies and asthma has increased, quite exponentially, during the last decades with WHO estimating above 400 million individuals debilitated by allergic rhinitis and 300 million by asthma; furthermore, 25-32% of European populations remain affected [1,2]. The postulated links between these conditions [3] demand a mandatory integration between to optimize treatment effects [2,4]. In some countries, up to 18% of people have asthma. Rates of many allergic diseases appear to be increasing. More than 150 million Europeans suffer from chronic allergic diseases and the current prediction is that by 2025 half of the entire EU population will be affected (EAACI, 2016).


Introduction
In the developed, industrial world, about 20% of people are affected by allergic rhinitis, about 6% of people have at least one food allergy, and about 20% have atopic dermatitis at some point in time. The global prevalence of allergies and asthma has increased, quite exponentially, during the last decades with WHO estimating above 400 million individuals debilitated by allergic rhinitis and 300 million by asthma; furthermore, 25-32% of European populations remain affected [1,2]. The postulated links between these conditions [3] demand a mandatory integration between to optimize treatment effects [2,4]. In some countries, up to 18% of people have asthma. Rates of many allergic diseases appear to be increasing. More than 150 million Europeans suffer from chronic allergic diseases and the current prediction is that by 2025 half of the entire EU population will be affected (EAACI, 2016). and anaphylactic shock). Hay fever (allergic rhinitis) is the most common of the allergic diseases and refers to seasonal nasal symptoms that are due to pollens. Year round or perennial allergic rhinitis is usually due to indoor allergens, such as dust mites or molds. The most common symptoms include runny nose, stuffy nose, sneezing, nasal itching (rubbing), itchy ears and throat and postnasal drip (throat clearing).
Asthma presents a chronic breathing problem those results from the allergic-inflammation and spasm of the lung's air passages (bronchial tubes). Asthma is most often, but not always, related to allergies. Common symptoms include shortness of breath, wheezing, coughing and chest tightness.
Allergic eyes (allergic conjunctivitis) is inflammation of the tissue layers (membranes) that cover the surface of the eyeball and the undersurface of the eyelid. The inflammation occurs a result of an allergic reaction. Common symptoms are redness under the lids and of the eye overall, watery, itchy eyes and swelling of the membranes.
Allergic eczema is an allergic rash that is usually not caused by skin contact with an allergen and features the following symptoms itching, redness, and or dryness of the skin, rash on the face, especially children and rash around the eyes, in the elbow creases, and behind the knees, especially in adults.
Hives (urticarial) are skin reactions that appear as itchy swellings and can occur on any part of the body. Hives can be caused by an allergic reaction, such as to a food or medication, but they also may occur in non-allergic people. Typical hive symptoms are raised red welts and intense itching.
Treatments for allergies include avoiding known allergens and the use of medications such as antihistamines and steroids. These may be in the form of pills or liquid, nasal sprays, or eyedrops. Although newer generation of antihistamines has improved, people may still experience side effects, such as headache, tiredness, dizziness, dry mouth, vision changes and excitability/nervousness. Side effects of corticosteroid nasal sprays include nosebleeds, stinging in the nose and dryness of the nose, nausea and dizziness.
In addition, several complementary health approaches have been studied for allergic rhinitis and there is some evidence that a few may be helpful. Probiotics (live microorganisms that may have health benefits) have been investigated for diseases of the immune system, including allergies. For example, JP 6 002 452 discloses a Saccharomyces cerevisiae yeast as useful for prevention and treatment of various immunological diseases by suppressing production of IgE causing type I allergy symptoms and JP 4 712 289 discloses a mixture of Saccharomyces and lactic acid bacteria for the prevention of food allergy. Although some studies have had promising results, the overall evidence on probiotics and allergic rhinitis is inconsistent.
opposed to intensive whereby the former would promote ameliorative effects and the latter worsened reactions, ought to be observed [6]. The positive interventional influences of physical exercise for dispositions of poor health, disorder and disease over a wide range of immunologically dependent parameter has been discussed comprehensively [7]. Suffice it to say that the influence of exercise among individuals suffering (i) acutely, and (ii) chronically, from allergic reactions may vary considerably. Physical exercise, despite presiding propensity to precipitate reactions depending on acute vs. chronic parameters, in the various forms of swimming, treadmill-running, aerobic or resistance, has been recommended for individuals prone to allergic rhinitis and/or asthma [8,9,10].In a longitudinal, randomized-control intervention study examining the potentially therapeutic effects of 'recreation winter exercise' upon a group of individuals presenting allergic airway inflammation expressing allergic rhinitis and asthma, estimations of quality-of-life, spirometry and cardiovascular fitness following a ten-day winter sports exercise program were derived. There were significant improvements in fractional oral exhaled nitric oxide accompanied by a significant decrease iron nitrate, and improvements in nasal eosinophilic cell counts due to exercise that prompted the conclusion of sustainable improvements in allergic symptoms. It has been demonstrated repeatedly that physical exercise combined with Milmed treatment over six to fourteen weeks induced a synergistic effect against symptoms of dopamine neurodegeneration [11,12]. The present account promotes the contention the physical exercise with accompanying Milmed treatment may offer a novel and viable alternative to anti-allergy interventions under current usage.

Conclusion
Treated yeast, Milmed, by itself or in combination with physical exercise programs may offer a novel viable alternative to current therapeutic alternatives available for ameliorating the problems and discomforts occasioned by allergens.